Fertility drugs and cancer: a guideline
| Autor: | Eric Widra, Alan S. Penzias, Robert W. Rebar, Randall R. Odem, Andrew La Barbera, Samantha M. Pfeifer, Daniel A. Dumesic, Samantha Butts, Richard J. Paulson, Michael Vernon, Jennifer Mersereau, Margareta D. Pisarska, Richard Reindollar, Clarisa R. Gracia, Mitchell P. Rosen, Gregory Fossum, Jay I. Sandlow |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Oncology medicine.medical_specialty Time Factors Reproductive Techniques Assisted medicine.drug_class media_common.quotation_subject Breast Neoplasms Fertility Risk Assessment 03 medical and health sciences 0302 clinical medicine Breast cancer Risk Factors Internal medicine Odds Ratio medicine Humans Age of Onset Aged Fertility drugs media_common Ovarian Neoplasms 030219 obstetrics & reproductive medicine business.industry Incidence Endometrial cancer Absolute risk reduction Obstetrics and Gynecology Cancer Fertility Agents Female Guideline Middle Aged medicine.disease Endometrial Neoplasms Treatment Outcome Reproductive Medicine Infertility 030220 oncology & carcinogenesis Female business Ovarian cancer |
| Zdroj: | Fertility and Sterility. 106:1617-1626 |
| ISSN: | 0015-0282 |
| Popis: | Methodological limitations in studying the association between the use of fertility drugs and cancer include the inherent increased risk of cancer in women who never conceive, the low incidence of most of these cancers, and that the age of diagnosis of cancer typically is many years after fertility drug use. Based on available data, there does not appear to be a meaningful increased risk of invasive ovarian cancer, breast cancer, or endometrial cancer following the use of fertility drugs. Several studies have shown a small increased risk of borderline ovarian tumors; however, there is insufficient consistent evidence that a particular fertility drug increases the risk of borderline ovarian tumors, and any absolute risk is small. Given the available literature, patients should be counseled that infertile women may be at an increased risk of invasive ovarian, endometrial, and breast cancer; however, use of fertility drugs does not appear to increase this risk. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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