Age-specific and sex-specific weight gain norms to monitor antiretroviral therapy in children in low-income and middle-income countries
| Autor: | Jamie E. Newman, Valériane Leroy, Sikiratou Koumakpai, Frieda Behets, Mary-Ann Davies, Marcel Yotebieng, Azar Kariminia, Rita Lyamuya, Kapella Zacharia Ngonyani, Rawiwan Hansudewechakul, Olivia Keiser, Annelies Van Rie, Tammy Meyers |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Percentile Anti-HIV Agents Immunology 610 Medicine & health HIV Infections Weight Gain Article 03 medical and health sciences 0302 clinical medicine Acquired immunodeficiency syndrome (AIDS) 360 Social problems & social services Reference Values Antiretroviral Therapy Highly Active medicine Humans Immunology and Allergy 030212 general & internal medicine Child Poverty Proportional Hazards Models 0303 health sciences 030306 microbiology business.industry Proportional hazards model Infant Viral Load medicine.disease CD4 Lymphocyte Count 3. Good health Infectious Diseases Child Preschool Normative Female Underweight medicine.symptom business Viral load Weight gain |
| Zdroj: | Yotebieng, Marcel; Meyers, Tammy; Behets, Frieda; Davies, Mary-Ann; Keiser, Olivia; Ngonyani, Kapella Zacharia; Lyamuya, Rita E; Kariminia, Azar; Hansudewechakul, Rawiwan; Leroy, Valeriane; Koumakpai, Sikiratou; Newman, Jamie; Van Rie, Annelies (2015). Age-specific and sex-specific weight gain norms to monitor antiretroviral therapy in children in low-income and middle-income countries. AIDS, 29(1), pp. 101-109. Lippincott Williams & Wilkins 10.1097/QAD.0000000000000506 AIDS |
| ISSN: | 0269-9370 |
| Popis: | BACKGROUND Viral load and CD4% are often not available in resource-limited settings for monitoring children's responses to antiretroviral therapy (ART). We aimed to construct normative curves for weight gain at 6, 12, 18, and 24 months following initiation of ART in children, and to assess the association between poor weight gain and subsequent responses to ART. DESIGN Analysis of data from HIV-infected children younger than 10 years old from African and Asian clinics participating in the International epidemiologic Databases to Evaluate AIDS. METHODS The generalized additive model for location, scale, and shape was used to construct normative percentile curves for weight gain at 6, 12, 18, and 24 months following ART initiation. Cox proportional models were used to assess the association between lower percentiles ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|