Metabolomics in drug discovery and development
| Autor: | U Frevert, D G Robertson |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Pharmacology
business.industry Drug discovery MEDLINE Translational medicine Target engagement Drug Evaluation Preclinical Computational biology Bioinformatics Metabolomics Drug Discovery Medicine Animals Humans Pharmacology (medical) Biomarker discovery business Media content Pharmaceutical industry |
| Zdroj: | Clinical pharmacology and therapeutics. 94(5) |
| ISSN: | 1532-6535 |
| Popis: | Metabolomics technology is being utilized across the spectrum of drug discovery and development; from the assessment of unanticipated biochemical sequelae of target engagement in transgenic models to monitoring media content to improve the efficiency of the manufacture of biologics, the impact of the technology is expanding dramatically. Applications critical for the pharmaceutical industry include translational medicine, biomarker discovery, and patient stratification. Technological innovation and cultural acceptance will be necessary to optimally use this powerful tool. |
| Databáze: | OpenAIRE |
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