Febrile illness and bicytopenia within hours after tick-borne encephalitis booster vaccination
| Autor: | Noemi Boos, Anne Leuppi-Taegtmeyer, Tim Bühler, Christoph Berger |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
lcsh:Immunologic diseases. Allergy Pediatrics medicine.medical_specialty Fever Immunology Pain Case Report Booster dose lcsh:RC254-282 03 medical and health sciences 0302 clinical medicine medicine Pharmacology (medical) Adjuvants Adverse effect Pharmacology Inactivated vaccines Leukopenia business.industry Tick-borne encephalitis medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Vaccination 030104 developmental biology Infectious Diseases Chills medicine.symptom Headaches business lcsh:RC581-607 Encephalitis Haematological diseases 030215 immunology |
| Zdroj: | npj Vaccines, Vol 4, Iss 1, Pp 1-3 (2019) NPJ Vaccines |
| ISSN: | 2059-0105 |
| Popis: | We report the case of a 20-year-old male complaining of sudden-onset, severe headaches, fever, chills, and generalized arthralgia. He had no symptoms of a respiratory tract infection. Blood examination revealed severe leukopenia and mild to moderate thrombocytopenia. Onset of symptoms was rapid, intense, and occurred only a few hours after routine tick-borne encephalitis (TBE) booster vaccine. The question of a relationship between booster vaccine administration and the febrile illness with bicytopenia was raised. A broad range of diagnostics excluded infections and other causes for bicytopenia. Symptoms resolved within a few days, and blood counts normalized within two weeks. Due to the close temporal relationship, a transient benign bicytopenia and febrile illness as a systemic reaction to TBE vaccination was assumed. Review of the literature and adverse event reporting systems suggest that this is a very rare reaction. |
| Databáze: | OpenAIRE |
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