Significant Changes Associated with the Transition from Outsourcing to In-hospital Therapeutic Drug Monitoring of Novel Antiepileptics
| Autor: | Akiko Kanaya, Daisuke Kobayashi, Satohiro Masuda, Kimitaka Suetsugu, Nanae Yamamoto, Yurie Nakayama, Tomohiro Shigematsu, Nobuaki Egashira, Yuichi Tsuchiya, Toshikazu Tsuji, Hiroyuki Watanabe |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Pharmacology
medicine.medical_specialty Time Factors medicine.diagnostic_test business.industry Pharmaceutical Science Outsourced Services Measurement cost Mass Spectrometry Outsourcing Therapeutic drug monitoring Emergency medicine Income medicine Humans Anticonvulsants Drug Monitoring Pharmacy Service Hospital business Chromatography Liquid |
| Zdroj: | YAKUGAKU ZASSHI. 140:1035-1040 |
| ISSN: | 1347-5231 0031-6903 |
| DOI: | 10.1248/yakushi.20-00001 |
| Popis: | For many of the novel antiepileptics, immunoassays, used for routine therapeutic drug monitoring (TDM), cannot be used. We could monitor eight novel antiepileptics using an LC/MS method since July 2017. The purpose of this study was to evaluate the significant changes associated with the transition from outsourcing to in-hospital monitoring of novel antiepileptics. The number of measurements of novel antiepileptics was significantly increased during the first (p |
| Databáze: | OpenAIRE |
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