A DOUBLE-BLINDED RANDOMIZED CONTROLLED TRIAL ON THE EFFECT OF FLAXSEED AND OLIVE OILS ON CONSTIPATION OF HEMODIALYSIS PATIENTS: PRELIMINARY RESULTS
| Autor: | Daniela G. Grilli, Lilian Cuppari, Maria Ayako Kamimura, Aline Fátima Andrade de Lima, Christiane Ishikawa Ramos, Giovana Sertori |
|---|---|
| Jazyk: | angličtina |
| Předmět: |
medicine.medical_specialty
Abdominal pain lcsh:Internal medicine Constipation lcsh:Specialties of internal medicine business.industry Double blinded Urology medicine.medical_treatment Initial dose Hard stools Gastroenterology law.invention Surgery Randomized controlled trial Nephrology law lcsh:RC581-951 Internal medicine medicine Defecation Hemodialysis medicine.symptom business lcsh:RC31-1245 |
| Zdroj: | Kidney Research and Clinical Practice, Vol 31, Iss 2, p A88 (2012) |
| ISSN: | 2211-9132 |
| DOI: | 10.1016/j.krcp.2012.04.610 |
| Popis: | Mineral oil has been used in the treatment of constipation in hemodialysis patients. Edible oils could also be a good option for treating this symptom. Therefore we aimed to investigate the effect of flaxseed and olive oils on constipation of hemodialysis patients. This trial was conducted for 4 weeks. Constipation was diagnosed by Rome III criterion. Thirty six constipated patients (18M, 51.0±12.2 years) were randomized into Mineral oil (MG; n=11), Flaxseed oil (FG; n=11) and Olive oil (OG; n=14) groups. The initial dose of each oil was 4 ml/d and was adjusted as needed. There was no difference in total oil used among groups (150.7±43.7 ml, 165.8±53.3 ml, 144.4±49.5 ml, respectively; p=0.61). The prevalence of each Roma III criterion item was similar among the groups. MG (%) OG (%) FG (%) 0 wk4 0 wk4 0 wk4 Abdominal pain 54.5 27.3 36.4 9.1 * 9.1 0 Straining on defecation 30.8 7.7 34.6 11.5 * 34.6 15.4 Lumpy or hard stools 32.3 9.7 39.7 12.9 29.0 12.9 Incomplete evacuation 28.1 18.8 43.8 28.1 28.1 18.8 Anorectal obstruction 29.2 12.5 45.8 4.2 * 25.0 12.5 Manual maneuvers 25.0 0 50.0 0 * 25.0 0 36.8 5.3 * 31.6 10.5 * 31.6 15.8 This preliminary result suggests that olive oil could be a healthy alternative on treatment of constipation in hemodialysis patients. ⁎ p |
| Databáze: | OpenAIRE |
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