Body Topography Parcellates Human Sensory and Motor Cortex
| Autor: | Pierre-Louis Bazin, Andreas Schäfer, Daniel S. Margulies, Juliane Dinse, Martin I. Sereno, Estrid Jakobsen, Xiangyu Long, Esther Kuehn, Arno Villringer |
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| Rok vydání: | 2017 |
| Předmět: |
innervation [Hand]
Male 0301 basic medicine Nerve net Somatosensory system Brain mapping diagnostic imaging [Sensorimotor Cortex] Myelin 0302 clinical medicine physiology [Sensorimotor Cortex] physiology [Movement] Neural Pathways Image Processing Computer-Assisted embodiment diagnostic imaging [Motor Cortex] Human Body Brain Mapping Motor Cortex Magnetic Resonance Imaging diagnostic imaging [Neural Pathways] hand–face border medicine.anatomical_structure innervation [Face] Female physiology [Nerve Net] Sensorimotor Cortex Primary motor cortex Psychology Motor cortex Adult Movement Cognitive Neuroscience physiology [Neural Pathways] Sensory system septa Young Adult 03 medical and health sciences Cellular and Molecular Neuroscience Physical Stimulation medicine Humans ddc:610 Resting state fMRI diagnostic imaging [Nerve Net] Original Articles Hand 030104 developmental biology physiology [Motor Cortex] parcellation plasticity Face Nerve Net Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Cerebral cortex 27(7), 3790-3805 (2017). doi:10.1093/cercor/bhx026 Cerebral Cortex (New York, NY) Cerebral Cortex |
| ISSN: | 1460-2199 1047-3211 |
| DOI: | 10.1093/cercor/bhx026 |
| Popis: | The cytoarchitectonic map as proposed by Brodmann currently dominates models of human sensorimotor cortical structure, function, and plasticity. According to this model, primary motor cortex, area 4, and primary somatosensory cortex, area 3b, are homogenous areas, with the major division lying between the two. Accumulating empirical and theoretical evidence, however, has begun to question the validity of the Brodmann map for various cortical areas. Here, we combined in vivo cortical myelin mapping with functional connectivity analyses and topographic mapping techniques to reassess the validity of the Brodmann map in human primary sensorimotor cortex. We provide empirical evidence that area 4 and area 3b are not homogenous, but are subdivided into distinct cortical fields, each representing a major body part (the hand and the face). Myelin reductions at the hand–face borders are cortical layer-specific, and coincide with intrinsic functional connectivity borders as defined using large-scale resting state analyses. Our data extend the Brodmann model in human sensorimotor cortex and suggest that body parts are an important organizing principle, similar to the distinction between sensory and motor processing. |
| Databáze: | OpenAIRE |
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