The influence of cross-linking time on the adsorption characteristics of microcapsules containing activated charcoal prepared by gelatin-acacia coacervation
| Autor: | Shunichi Noro, Fumiyoshi Ishii, Katsuhiko Saegusa |
|---|---|
| Rok vydání: | 1985 |
| Předmět: |
food.ingredient
Time Factors Chemical Phenomena Capsules Gelatin Gum Arabic Adsorption food Polysaccharides Drug Discovery medicine Semipermeable membrane Chromatography Coacervate Chemistry General Chemistry General Medicine Cross-Linking Reagents Activated charcoal Charcoal Activated charcoal powder Activated carbon medicine.drug |
| Zdroj: | Chemicalpharmaceutical bulletin. 33(11) |
| ISSN: | 0009-2363 |
| Popis: | In this study, the effect of cross-linking time on the adsorption characteristics of microcapsules containing activated charcoal (ACMC) was investigated. The microcapsules were prepared by the gelatin-acacia coacervation procedure. Activated charcoal powder was used as an adsorbent, and creatinine as a model adsorbate. The following results were obtained. The adsorption rate on ACMC could be controlled by changing the cross-linking time of the coacervate. A stable semipermeable membrane was formed by gelatin-acacia coacervation at cross-linking times greater than 60 min. Accordingly, the oral administration of ACMC should be available as a supporting technique in the treatment of patients with renal failure. |
| Databáze: | OpenAIRE |
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