Dosimetric assessment of an Atlas based automated segmentation for loco-regional radiation therapy of early breast cancer in the Skagen Trial 1: A multi-institutional study
| Autor: | M.H. Nielsen, Carine Kirkove, Birgitte Vrou Offersen, Giulio Francolini, Zahra Taheri-Kadkhoda, T.B. Nyeng, M.S. Thomsen, Ahmed R Eldesoky, Egil S. Blix, Martin Berg, E.S. Yates, Claus Kamby |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Dose-volume histogram medicine.medical_treatment R895-920 Automated segmentation Article 030218 nuclear medicine & medical imaging Medical physics. Medical radiology. Nuclear medicine 03 medical and health sciences 0302 clinical medicine Atlas (anatomy) Skagen Trial 1 medicine Radiology Nuclear Medicine and imaging In patient Medical physics RC254-282 Early breast cancer business.industry fungi Neoplasms. Tumors. Oncology. Including cancer and carcinogens food and beverages Clinical Practice Radiation therapy medicine.anatomical_structure Oncology 030220 oncology & carcinogenesis Manual segmentation Radiology business |
| Zdroj: | Clinical and Translational Radiation Oncology Eldesoky, A R, Francolini, G, Thomsen, M S, Yates, E S, Nyeng, T B, Kirkove, C, Kamby, C, Blix, E S, Nielsen, M H, Taheri-Kadkhoda, Z, Berg, M & Offersen, B V 2017, ' Dosimetric assessment of an Atlas based automated segmentation for loco-regional radiation therapy of early breast cancer in the Skagen Trial 1 : A multi-institutional study ', Clinical and Translational Radiation Oncology, vol. 2, pp. 36-40 . https://doi.org/10.1016/j.ctro.2017.01.004 Clinical and Translational Radiation Oncology, Vol 2, Iss C, Pp 36-40 (2017) Ibrahim, A R M E, Francolini, G, Thomsen, M S, Yates, E S, Nyeng, T B, Kirkove, C, Kamby, C, Blix, E S, Nielsen, M H, Taheri-Kadkhoda, Z, Berg, M & Offersen, B V 2017, ' Dosimetric assessment of an Atlas based automated segmentation for loco-regional radiation therapy of early breast cancer in the Skagen Trial 1: A multi-institutional study ', Clinical and Translational Radiation Oncology, vol. 2, pp. 36-40 . https://doi.org/10.1016/j.ctro.2017.01.004 |
| ISSN: | 2405-6308 |
| DOI: | 10.1016/j.ctro.2017.01.004 |
| Popis: | Highlights • 40 dose plans from the Skagen Trial 1 collected from Denmark, Belgium and Norway. • Atlas-based automated segmentation of each CT scan was obtained using MIM Maestro™. • DSC and difference in volume with manual segmentation were collected. • HI, V95 and V90% measured on the two different segmentations were compared. • Inter-observer variability was low and dose parameters were comparable. The effect of Atlas-based automated segmentation (ABAS) on dose volume histogram (DVH) parameters compared to manual segmentation (MS) in loco-regional radiotherapy (RT) of early breast cancer was investigated in patients included in the Skagen Trial 1. This analysis supports implementation of ABAS in clinical practice and multi-institutional trials. |
| Databáze: | OpenAIRE |
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