Dynamics of Organization of the Microcirculatory Bed and Mast Cells of the Uterus in Rats at Different Times of the Day
| Autor: | A. E. Kotsyuba, V. M. Chertok, I. A. Khramova |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Cell signaling Uterus Endometrium General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Internal medicine Microcirculatory Bed medicine Animals Mast Cells Mast (botany) Rats Wistar Receptor Structural organization Gasotransmitters Chemistry Microcirculation Dynamics (mechanics) General Medicine Rats 030104 developmental biology medicine.anatomical_structure Endocrinology Female Nitric Oxide Synthase NADP 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 169:710-713 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-020-04961-z |
| Popis: | Structural organization of the microcirculatory bed and mast cells in the uterus of mature female Wistar rats (n=60) were examined every 2 h over 24 h. During night hours, many vessels characterized by intensive reaction to NADPH-diaphorase and endothelial NO synthase were detected in the endometrium, and the density of these vessels and mast cells was quite high. During the day and evening hours, the capillaries with high levels of enzymes involved in NO synthesis and mast cells were less numerous. NO directly regulating the diameter of arteries and the intensity of transcapillary exchange can act as a signal molecule in the temporal dynamics of the vasoceptive action of estrogens and their receptors in the uterus. |
| Databáze: | OpenAIRE |
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