DKA cases over the last three years: has anything changed?
| Autor: | Natalia G. Vallianou, Barbara Vlassopoulou, George Ioannidis, Stylianos Tsagarakis, Theodora Stratigou, M. Tzanela, Dimitra Vassiliadi |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Time Factors endocrine system diseases Diabetic ketoacidosis Adolescent Endocrinology Diabetes and Metabolism 030209 endocrinology & metabolism Context (language use) Disease Type 2 diabetes Diabetic Ketoacidosis 03 medical and health sciences Young Adult 0302 clinical medicine Diabetes mellitus Internal Medicine Prevalence Medicine Humans 030212 general & internal medicine Aged Retrospective Studies Aged 80 and over Type 1 diabetes Greece business.industry nutritional and metabolic diseases General Medicine Middle Aged medicine.disease Prognosis Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Cohort Etiology Female business Biomarkers Follow-Up Studies |
| Zdroj: | Diabetesmetabolic syndrome. 13(2) |
| ISSN: | 1878-0334 |
| Popis: | Background Diabetic ketoacidosis (DKA) has been related mainly to type 1 diabetes mellitus (T1DM). However, it is not solely related to T1DM. The purpose of this study was to assess the prevalence of DKA among type 1 and type 2 patients with diabetes mellitus, who were hospitalized in our Clinic due to DKA, as well as to determine the etiology beyond DKA. Patients and methods A cohort of 109 patients with DKA, 17–86 years of age, who were hospitalized in the Department of Endocrinology, Diabetes and Metabolism of our hospital between 2015 and 2017, were included in the study. Results Among the 109 patients, 50 (45.9%) had mild DKA, 48 (44.1%) had moderate DKA, whereas 11 patients (10%) had severe DKA. Sixty-five patients (60%) developed DKA as the first manifestation of T1DM, 30 patients (27%) developed DKA in the context of type 2 diabetes (T2DM), mainly due to the co-existence of serious infections, 11 patients (10%) had T1DM, but had omitted their insulin dosages, and 3 patients (3%) developed DKA due to unknown reasons. Conclusions Most patients with DKA presented with mild and moderate DKA and only a minority presented with the severe form of the disease. The etiology of DKA was mainly T1DM and less frequent uncontrolled T2DM, usually due to the co-existence of severe infections, while only in a tiny minority, the causes remained unidentifiable. |
| Databáze: | OpenAIRE |
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