The rashes that lead to cutaneous ulcers
| Autor: | Marcia Ramos-e-Silva, Amanda Pedreira Nunes, Sueli Carneiro |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Vasculitis
medicine.medical_specialty Cutaneous ulceration Paraneoplastic Syndromes Hepatosplenomegaly Dermatology Infections Autoimmune Diseases 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Skin Ulcer Parasitic Diseases medicine Humans Exanthem 030203 arthritis & rheumatology Granuloma Skin Diseases Vesiculobullous business.industry Exanthema medicine.disease Sweet Syndrome Rash Cutaneous ulcers Drug Hypersensitivity Syndrome Etiology medicine.symptom business |
| Zdroj: | Clinics in Dermatology. 38:42-51 |
| ISSN: | 0738-081X |
| DOI: | 10.1016/j.clindermatol.2019.10.021 |
| Popis: | Skin rashes have exanthema as a synonym, a term derived from the Greek words exanthem, meaning "to appear," and anthos, which denotes "flourishing." The relevant factors for characterization of a rash include distribution, configuration, and organization of the lesions, in addition to evidence of systemic involvement through toxemia, adenopathy, and conjunctive lesions, hepatosplenomegaly, excoriations or phlogosis, neck rigidity, or neurologic dysfunction. A rash may evolve to cutaneous ulceration in many instances, which is relevant for the diagnosis, the followup, and the therapeutic management of the patient. Systemic diseases with exanthemas that result in ulcerations prevail over diseases that are restricted to signs and/or merely cutaneous clinical manifestations. A variety of etiologies can present cutaneous rashes with ulcers, subject or not to systemic involvement by the underlying disease, among which stand out the bullous diseases, infectious and parasitic diseases, noninfectious granulomatous diseases, vasculitis, paraneoplastic syndromes, autoimmune diseases of the connective tissue, neutrophilic diseases, lichen planus, and drug hypersensitivity syndrome. The authors present a detailed review of some diseases corresponding to each one of the mentioned etiologies, updating the clinical manifestations and therapeutic proposals. |
| Databáze: | OpenAIRE |
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