Detection of theophylline using molecularly imprinted mesoporous silica spheres
| Autor: | Dongyun Zheng, Jiebin Li, Hai-Bo Wang, Aixia Zhao, Yan-Ming Liu, Tian Gan, Jiahui Xu |
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| Rok vydání: | 2018 |
| Předmět: |
Materials science
Polymers 02 engineering and technology Polypyrrole 01 natural sciences Analytical Chemistry Molecular Imprinting chemistry.chemical_compound Electron transfer Theophylline Limit of Detection Pyrroles Electrodes Sol-gel Detection limit 010401 analytical chemistry Molecularly imprinted polymer General Medicine Mesoporous silica Silicon Dioxide 021001 nanoscience & nanotechnology 0104 chemical sciences Membrane chemistry Chemical engineering Electrode 0210 nano-technology Nanospheres Food Science |
| Zdroj: | Food Chemistry. 268:1-8 |
| ISSN: | 0308-8146 |
| DOI: | 10.1016/j.foodchem.2018.06.058 |
| Popis: | Here, we report a three-dimensional (3D) network molecularly imprinted polymer (MIP) on electrode surface to achieve an efficient and specific detection of theophylline in foodstuffs, using theophylline as the template molecule, mesoporous silica nanospheres (MSNs) as the signal transducer to shuttle electrons, and both phenyltriethoxysilane and pyrrole as functional monomers. The electron microscope images reveal the presence of well-distributed hierarchically MSNs with a pomegranate-like morphology, topped with MIP uniform layer. Electrochemical characterizations were carried out to monitor the properties of the resulting sensing platform based on the MIP/gate effect employing hexacyanoferrate molecules as the electrochemical probe. The data show that due to the high conductivity and electron transfer ability of the prepared theophylline-imprinted membrane, this method exhibits excellent sensitivity and binding affinity with a linear dynamic concentration range in excess of six orders of magnitude and low detection limit (0.66 nM), meeting the requirements of theophylline trace analysis. |
| Databáze: | OpenAIRE |
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