Iodine-Promoted Deoxygenative Iodization/Olefination/Sulfenylation of Ketones with Sulfonyl Hydrazides: Access to β-Iodoalkenyl Sulfides
| Autor: | Xiuqin Yang, Qingfa Zhou, Yishu Bao, Fulai Yang |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Sulfonyl
chemistry.chemical_classification 010405 organic chemistry Chemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry Iodine 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences chemistry.chemical_compound Vinyl iodide Stereoselectivity Organic synthesis Physical and Theoretical Chemistry |
| Zdroj: | Organic Letters. 20:1966-1969 |
| ISSN: | 1523-7052 1523-7060 |
| DOI: | 10.1021/acs.orglett.8b00511 |
| Popis: | A highly regio- and stereoselective synthesis of β-haloalkenyl sulfides using commercially available ketones and sulfonyl hydrazides as starting materials has been developed. This protocol obviates the need for alkynes and traditional sulfenylating agents and therefore opens up a new door to construct β-iodoalkenyl sulfides in a highly simple manner. This study reveals that ketones could be used as vinyl iodide precursors in organic synthesis. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|