Neuropsychological effects and cognitive deficits associated with exposure to mercury and arsenic in children and adolescents of the Mojana region, Colombia
| Autor: | César Argumedos De la Ossa, Andrés Fernando Ramírez-Giraldo, Katy Arroyo-Alvis, José Marrugo-Negrete, Sergi Díez |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
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| Popis: | The present study aims to explore the neuropsychological performance and exposure to mercury (Hg) and arsenic (As) in Colombian children and adolescents considering biomarkers in hair and blood. The total sample consisted of 70 participants from the Mojana region, Colombia. A neuropsychological evaluation protocol was used, consisting of 11 internationally recognized tests, with evidence of national validation and use for measurement in neurotoxicology contexts. A 57.1% of the sample presented levels above the reference value according to the USEPA, the WHO, and the ATSDR for total mercury in hair (HgH), blood mercury (HgB), and/or blood arsenic (AsB). The mean values reported for HgH were 1.76 ± 3.1 μg/g (95% CI 1.02-2.50) with ranges between 0.23 and 17.20; for HgB: 4.11 ± 5.93 μg/l (CI 2.69-5.52), ranging between 0.25 and 25.80, and for AsB: 1.96 ± 2.73 (CI 1.31-2.61) ranging between 0.50 and 15.50. In the comparison of groups in relation to the level of exposure, a significant difference was found (p The authors wish to thank the Ministry of Science of Colombia (Minciencias) for funding the internship grant under the “Young Researchers and Innovators” program (Call 775) and to the research groups Human Dimensions (Corporación Universitaria del Caribe-CECAR, Colombia) and Water, Applied and Environmental Chemistry (University of Córdoba, Colombia) who made possible the realization of this study. The authors would also like to acknowledge the Spanish National Research Council (CSIC) through project iCOOP+2018-COOPB20362 and the CYTED (Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo), for financing the MercuRed Network (420RT0007). |
| Databáze: | OpenAIRE |
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