A study of gastrointestinal cancer-associated antigen (GICA) in human fetal organs
| Autor: | Hilary Koprowski, Marie-Claude Fondaneche, Hélène Raux, Pierre Burtin, François Labbe |
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| Rok vydání: | 1983 |
| Předmět: |
Immunofixation
Cancer Research Pathology medicine.medical_specialty medicine.drug_class Fluorescent Antibody Technique Neuraminidase Monoclonal antibody Antigen Antigens Neoplasm Pregnancy medicine Humans Gastrointestinal cancer Gastrointestinal Neoplasms Glycoproteins chemistry.chemical_classification Fetus biology Antibodies Monoclonal medicine.disease Oncology chemistry Pronase embryonic structures Human fetal Immunology biology.protein Female Glycoprotein Digestive System |
| Zdroj: | International journal of cancer. 32(3) |
| ISSN: | 0020-7136 |
| Popis: | The gastrointestinal cancer-associated antigen (GICA) characterized by 1116 NS 19-9 monoclonal antibody was studied in human fetal organs by immunohistology and immunofixation on nitrocellulose sheets. It was found in all the gastrointestinal tracts of fetuses and newborns. Other fetal organs, except biliary and pancreatic ducts, were negative. Immunohistological data and enzymatic studies led us to conclude that GICA is predominantly a mucin-type glycoprotein in fetal organs. |
| Databáze: | OpenAIRE |
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