Effects of treatment of peripheral pain generators in fibromyalgia patients
| Autor: | Domenico Lapenna, Raffaele Costantini, Maria Adele Giamberardino, Emmanuele Tafuri, Alessandra Fabrizio, Giannapia Affaitati |
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| Rok vydání: | 2010 |
| Předmět: |
Adult
Pain Threshold medicine.medical_specialty Fibromyalgia Time Factors Adolescent Comorbidity Myofascial pain syndrome Placebo Severity of Illness Index law.invention Young Adult Randomized controlled trial law Severity of illness medicine Humans Anesthetics Local Muscle Skeletal Myofascial Pain Syndromes Aged Pain Measurement business.industry Middle Aged medicine.disease Arthralgia Surgery Peripheral Anesthesiology and Pain Medicine Treatment Outcome Joint pain Anesthesia Female medicine.symptom business Follow-Up Studies |
| Zdroj: | European journal of pain (London, England). 15(1) |
| ISSN: | 1532-2149 |
| Popis: | Fibromyalgia syndrome (FS) frequently co-occurs with regional pain disorders. This study evaluated how these disorders contribute to FS, by assessing effects of local active vs placebo treatment of muscle/joint pain sources on FS symptoms. Female patients with (1) FS+myofascial pain syndromes from trigger points (n=68), or (2) FS+joint pain (n=56) underwent evaluation of myofascial/joint symptoms [number/intensity of pain episodes, pressure pain thresholds at trigger/joint site, paracetamol consumption] and FS symptoms [pain intensity, pressure pain thresholds at tender points, pressure and electrical pain thresholds in skin, subcutis and muscle in a non-painful site]. Patients of both protocols were randomly assigned to two groups [34 each for (1); 28 each for (2)] to receive active or placebo local TrP or joint treatment [injection/hydroelectrophoresis] on days 1 and 4. Evaluations were repeated on days 4 and 8. After therapy, in active--but not placebo-treated-- groups: number and intensity of myofascial/joint episodes and paracetamol consumption decreased and pressure thresholds at trigger/joint increased (p |
| Databáze: | OpenAIRE |
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