Risk factors for massive blood transfusion in cytoreductive surgery: a multivariate analysis of 243 procedures
| Autor: | Khaled Al-Mohaimeed, Sal Fransi, David L. Morris, Tristan D. Yan, Sulman Ahmed, Terence C. Chua, Akshat Saxena |
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| Rok vydání: | 2009 |
| Předmět: |
Male
medicine.medical_specialty Multivariate analysis Blood transfusion medicine.medical_treatment Blood Loss Surgical law.invention Blood Transfusion Autologous Postoperative Complications law Peritonectomy Risk Factors Antineoplastic Combined Chemotherapy Protocols medicine Humans Peritoneal Neoplasms Neoplasm Staging Chemotherapy business.industry Cancer Perioperative Hyperthermia Induced Middle Aged medicine.disease Prognosis Intensive care unit Combined Modality Therapy Surgery Treatment Outcome Oncology Anesthesia Chemotherapy Cancer Regional Perfusion Female Morbidity Packed red blood cells business Erythrocyte Transfusion |
| Zdroj: | Annals of surgical oncology. 16(8) |
| ISSN: | 1534-4681 |
| Popis: | Cytoreductive surgery (CRS) combined with perioperative intraperitoneal chemotherapy (PIC) has demonstrated improved survival in selected patients with peritoneal carcinomatosis (PC). This treatment modality is associated with high blood loss and often requires massive allogenic red blood cell transfusion (MABT). Our study is the first of its kind to evaluate the risk factors for intraoperative MABT in peritonectomy procedures. Two hundred and forty-three consecutive CRS and PIC procedures were evaluated. The associations between 17 preoperative and intraoperative risk factors and intraoperative MABT (≥6 units) were assessed by univariate and multivariate analysis. One hundred and eighty-six (77%) procedures required intraoperative transfusion of packed red blood cells. Ninety-one procedures required MABT (37%). Multivariate analysis showed six significant risk factors for intraoperative MABT: operative length > 9 h (p |
| Databáze: | OpenAIRE |
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