JC Papovavirus in Progressive Multifocal Leukoencephalopathy
| Autor: | Duard L. Walker, A. E. Hodach, Gabriele M. ZuRhein, Billie L. Padgett, S. M. Chou |
|---|---|
| Rok vydání: | 1976 |
| Předmět: |
Adult
Male Virus Cultivation viruses JC virus Fluorescent Antibody Technique Immunofluorescence medicine.disease_cause Virus Leukoencephalopathy Tissue culture Cytopathogenic Effect Viral medicine Humans Immunology and Allergy Serotyping Antigens Viral Papillomaviridae Cells Cultured Hemagglutination Viral medicine.diagnostic_test biology Progressive multifocal leukoencephalopathy Leukoencephalopathy Progressive Multifocal Brain Middle Aged biology.organism_classification medicine.disease Virology Polyomaviridae Infectious Diseases Female Papovavirus |
| Zdroj: | Journal of Infectious Diseases. 133:686-690 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/133.6.686 |
| Popis: | Brain tissue from seven patients with progressive multifocal leukoencephalopathy was tested for the presence of papovaviruses. JC virus, ahuman papovavirus, was identified in all seven cases. Virus was isolated in tissue culture from extracts from each of four patients and was detected by immunofluorescence in sections from the other three. The new osolates were indistinguishable from the prototypical JC strain serologically and in all biological characteristics examined. Thus JC virus has, to date, been associated with 20 cases of progressive multifocal leukoencephalopathy. |
| Databáze: | OpenAIRE |
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