Effects of maternal high fat intake during pregnancy and lactation on total cholesterol and adipose tissue in neonatal rats
| Autor: | Jairza Maria Barreto-Medeiros, Gabriela dos Santos Perez, G. L. Morais, M. S. Lima, Carol Góis Leandro, G. S. Cordeiro, T. C. B. J. Deiró, Ricardo David Couto, L. S. Santos |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
0301 basic medicine
ratos neonatos Adipose tissue Physiology chemistry.chemical_compound 0302 clinical medicine Pregnancy tecido adiposo visceral lcsh:Botany Lactation lcsh:Zoology lcsh:QL1-991 visceral adipose tissue lcsh:Science lcsh:QH301-705.5 neonatal rats high fat diet colesterol Lipids lcsh:QK1-989 Cholesterol medicine.anatomical_structure Adipose Tissue Prenatal Exposure Delayed Effects Female medicine.symptom General Agricultural and Biological Sciences Offspring 030209 endocrinology & metabolism Biology Diet High-Fat 03 medical and health sciences medicine High fat Animals Obesity Rats Wistar dieta hiperlipídica 030109 nutrition & dietetics cholesterol medicine.disease Rats Disease Models Animal Animals Newborn lcsh:Biology (General) chemistry Pregnancy Animal lcsh:Q Weight gain |
| Zdroj: | Brazilian Journal of Biology v.78 n.4 2018 Brazilian Journal of Biology Instituto Internacional de Ecologia (IIE) instacron:IIE Brazilian Journal of Biology, Issue: ahead, Published: 08 JAN 2018 Brazilian Journal of Biology, Iss 0 (2018) |
| ISSN: | 1678-4375 1519-6984 |
| DOI: | 10.1590/1519-6984.166788 |
| Popis: | Aim Obesity during pregnancy is one of the most established risk factors for negative long-term programming. The aim of the present study was to investigate the effects of maternal consumption of a high-fat diet during pregnancy and lactation on the weight gain, visceral adipose tissue and cholesterolemia in neonatal rats. Methods Wistar rats were divided into two groups according to the mother's diet during pregnancy and lactation: Control group (CG, n = 12) were the offspring of rats fed a standard diet (4% lipid) and the Test group (TG, n = 12) were pups rats fed on a high fat diet (23% lipid). The weight of the animals was measured on alternate days until the 22nd day of life, when collected visceral adipose tissue and blood were collected for biochemical analysis. For statistical analysis the Student t test, Sidak´s teste and two way ANOVA was used, with p |
| Databáze: | OpenAIRE |
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