Effect of zinc therapy on natural killer cell activity in inflammatory bowel disease
| Autor: | C. B. H. W. Lamers, Amado Salvador Peña, A. Van Der Sluys Veer, E. A. F. Van Tol, Gerrit Griffioen, Y. Van De Wal, H. W. Verspaget, T. P. J. Mulder |
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| Rok vydání: | 2007 |
| Předmět: |
Adult
Male Cell Survival medicine.medical_treatment Inflammatory bowel disease Natural killer cell Immune system Stable Disease Crohn Disease Double-Blind Method In vivo Oral administration medicine Humans Pharmacology (medical) Colitis Chemotherapy Hepatology business.industry Gastroenterology Inflammatory Bowel Diseases medicine.disease Diet Killer Cells Natural Zinc medicine.anatomical_structure Immunology Colitis Ulcerative Female business |
| Zdroj: | Alimentary Pharmacology & Therapeutics. 7:281-286 |
| ISSN: | 1365-2036 0269-2813 |
| DOI: | 10.1111/j.1365-2036.1993.tb00099.x |
| Popis: | Disturbances in zinc metabolism have been documented in patients with inflammatory bowel disease. In this study we evaluated the effect of in vivo treatment with zinc on the in vitro natural killer cell activity in thirteen inflammatory bowel disease patients, with stable disease and mild-moderate disease activity, in a double-blind randomized cross-over trial. The results of our study show a long-lasting effect of in vivo zinc administration, which decreased peripheral blood natural killer cell activity in inflammatory bowel disease. |
| Databáze: | OpenAIRE |
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