Chronic kidney disease and cardiovascular risk in hypertensive type 2 diabetics: a primary care perspective
| Autor: | Michela Re, Giuseppe Noberasco, Giacomo Deferrari, Rossella Cannavò, Maura Ravera, Alessandro Filippi, Claudio Cricelli, Anna Maria Gallina, Ursula Weiss, Giambattista Ravera |
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| Jazyk: | angličtina |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Population Renal function Blood Pressure Type 2 diabetes urologic and male genital diseases Electrocardiography Risk Factors Internal medicine Diabetes mellitus medicine Humans Risk factor education Antihypertensive Agents Aged Retrospective Studies Aged 80 and over Transplantation education.field_of_study Primary Health Care business.industry Middle Aged Prognosis medicine.disease female genital diseases and pregnancy complications Surgery Blood pressure Diabetes Mellitus Type 2 Italy Cardiovascular Diseases Nephrology Chronic Disease Hypertension Multivariate Analysis Female Kidney Diseases Hemodialysis business Glomerular Filtration Rate Kidney disease |
| Popis: | Background. Chronic kidney disease (CKD) is associated with poor renal and cardiovascular (CV) outcome, and early identification largely depends on the general practitioners' (GPs) awareness of it. Only a few studies have evaluated the prevalence of CKD in type 2 diabetes in primary care, and no studies are available on hypertensive diabetics. Thus, the aim of this study was to assess the prevalence of CKD and its association with CV morbidity in such a population. Methods. On the basis of an Italian national project involving GPs and nephrologists, we retrieved demographic, laboratory and clinical data regarding 7582 hypertensive type 2 diabetics (3564 men; age 25-89 years) who were selected using the diagnostic code Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) for diabetes and hypertension. Blood pressure (BP) values, serum creatinine, ECG-diagnosed left ventricular hypertrophy (LVH) and the occurrence of previous major CV events were obtained for each patient from the GPs' Health Search Database. Estimated glomerular filtration rate (GFR) was calculated according to the four-variable MDRD equation. CKD was defined as an estimated GFR < 60 mL/min/ 1.73 m 2 . Results. CKD prevalence was 26%, although renal disease was diagnosed by GPs in only 5.4% of cases. The prevalence of both LVH and major CV events was 8%. Adequate BP control was only achieved in 10.4% of patients. Patients whose GFR was |
| Databáze: | OpenAIRE |
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