Antidepressant use in pregnancy and severe cardiac malformations: Danish register‐based study
| Autor: | Vera Ehrenstein, Lars Pedersen, Lars H Pedersen, Olav Bjørn Petersen, Line Kolding, Puk Sandager, Niels Uldbjerg |
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| Rok vydání: | 2021 |
| Předmět: |
Adult
Heart Defects Congenital Male prenatal ultrasound medicine.medical_specialty Denmark Population Venlafaxine Miscarriage 03 medical and health sciences 0302 clinical medicine Pregnancy venlafaxine medicine Humans SSRI selection bias Registries education education.field_of_study 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Obstetrics Infant Newborn Venlafaxine Hydrochloride Absolute risk reduction Abnormalities Drug-Induced Obstetrics and Gynecology Prenatal Care Antidepressants Number needed to harm medicine.disease Antidepressive Agents Pregnancy Complications Prenatal Exposure Delayed Effects Female pregnancy business Live birth Fetal echocardiography Selective Serotonin Reuptake Inhibitors medicine.drug |
| Zdroj: | Kolding, L, Ehrenstein, V, Pedersen, L, Sandager, P, Petersen, O B, Uldbjerg, N & Pedersen, L H 2021, ' Antidepressant use in pregnancy and severe cardiac malformations : Danish register-based study ', BJOG: An International Journal of Obstetrics and Gynaecology, vol. 128, no. 12, pp. 1949-1957 . https://doi.org/10.1111/1471-0528.16772 Kolding, L, Ehrenstein, V, Pedersen, L, Sandager, P, Petersen, O B, Uldbjerg, N & Pedersen, L H 2021, ' Antidepressant use in pregnancy and severe cardiac malformations : Danish register-based study ', BJOG: An International Journal of Obstetrics and Gynaecology . https://doi.org/10.1111/1471-0528.16772 Kolding, L, Ehrenstein, V, Pedersen, L, Sandager, P, Petersen, OB, Uldbjerg, N & Pedersen, LH 2021, ' Antidepressant use in pregnancy and severe cardiac malformations : Danish register-based study ', BJOG: An International Journal of Obstetrics & Gynaecology, vol. 128, no. 12, pp. 1949-1957 . https://doi.org/10.1111/1471-0528.16772 |
| ISSN: | 1471-0528 1470-0328 |
| DOI: | 10.1111/1471-0528.16772 |
| Popis: | Objective: Studies restricted to live births may underestimate severe teratogenic effects. We address the limitation by including data from both prenatal and postnatal diagnoses of cardiac malformations. Design: Register-based study. Setting: Denmark. Population: 364 012 singleton pregnancies from 2007 to 2014. Methods: We used data from five nationwide registries. Exposure to antidepressants was measured using redeemed prescriptions. Main outcome measures: Pregnancies with cardiac malformations that end in miscarriage, termination, stillbirth, postnatal death or cardiac surgery |
| Databáze: | OpenAIRE |
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