A network meta-analysis on the comparative efficacy of different dietary approaches on glycaemic control in patients with type 2 diabetes mellitus
Autor: | Georg F. Hoffmann, Anna Chaimani, Carolina Schwedhelm, Lukas Schwingshackl, Heiner Boeing |
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Rok vydání: | 2017 |
Předmět: |
Adult
Blood Glucose medicine.medical_specialty Mediterranean diet Epidemiology Network Meta-Analysis Psychological intervention 030209 endocrinology & metabolism Type 2 diabetes Diet Mediterranean law.invention 03 medical and health sciences Diet Carbohydrate-Restricted 0302 clinical medicine Randomized controlled trial law Internal medicine Diabetes mellitus Type 2 diabetes mellitus medicine Humans 030212 general & internal medicine Randomized Controlled Trials as Topic Glycated Hemoglobin business.industry Type 2 Diabetes Mellitus medicine.disease Diet Diabetes Mellitus Type 2 Evidence synthesis Meta-analysis Systematic review Female business Meta-Analysis Diet Therapy |
Zdroj: | European Journal of Epidemiology |
ISSN: | 1573-7284 |
Popis: | The aim of the present study is to assess the comparative efficacy of different dietary approaches on glycaemic control in patients with type 2 diabetes mellitus using a systematic review of the literature. Electronic and hand searches were performed until July 2017. The inclusion criteria were defined as follows: (1) randomized trial with a dietary approach; (2) adults with type 2 diabetes mellitus; (3) outcome either HbA1c (%) and/or fasting glucose (mmol/l); (4) minimum intervention period of 12 weeks. For each outcome measure, random effects network meta-analysis was performed in order to determine the pooled effect of each intervention relative to each of the other interventions. A total of 56 trials comparing nine dietary approaches (low-fat, Vegetarian, Mediterranean, high-protein, moderate-carbohydrate, low-carbohydrate, control, low GI/GL, Palaeolithic) enrolling 4937 participants were included. For reducing HbA1c, the low-carbohydrate diet was ranked as the best dietary approach (SUCRA: 84%), followed by the Mediterranean diet (80%) and Palaeolithic diet (76%) compared to a control diet. For reducing fasting glucose, the Mediterranean diet (88%) was ranked as the best approach, followed by Palaeolithic diet (71%) and Vegetarian diet (63%). The network analysis also revealed that all dietary approaches significantly reduce HbA1c (− 0.82 to − 0.47% reduction) and fasting glucose (− 1.61 to − 1.00 mmol/l reduction) compared to a control diet. According to the network meta-analysis the Mediterranean diet is the most effective and efficacious dietary approach to improve glycaemic control in type 2 diabetes patients. Electronic supplementary material The online version of this article (10.1007/s10654-017-0352-x) contains supplementary material, which is available to authorized users. |
Databáze: | OpenAIRE |
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