Bilateral Phlegmasia Cerulea Dolens After Warfarin Reversal for Acute Rectal Bleeding: A Case Report
| Autor: | Burr Fong, Michael Dalley, Daniel Novak, Gregory Alfred |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Vitamin K Deep vein Hemorrhage 030204 cardiovascular system & hematology Venous stasis 03 medical and health sciences 0302 clinical medicine medicine Humans cardiovascular diseases Phlegmasia cerulea dolens Ultrasonography Aged 80 and over Venous Thrombosis business.industry Warfarin Rectum Anticoagulants medicine.disease Thrombosis Surgery Pulmonary embolism Venous thrombosis medicine.anatomical_structure Lower Extremity Emergency Medicine Phlegmasia alba dolens Female business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | The Journal of emergency medicine. 54(4) |
| ISSN: | 0736-4679 |
| Popis: | Background Deep vein thrombosis (DVT) is a common disease that is diagnosed in approximately 1 in 1000 adults annually. Extensive DVT can lead to life- or limb-threatening diagnoses such as phlegmasia cerulea dolens (PCD), phlegmasia alba dolens, and venous gangrene. PCD, also known as massive iliofemoral venous thrombosis, is rare, and a severe complication of DVT. Case Report We report a case of a 94-year-old bedridden woman with past medical history of dementia, hypertension, pulmonary embolism, DVT, and atrial fibrillation. The patient was admitted to the hospital for bright red blood per rectum and an elevated international normalized ratio (INR) of 5.7. On admission, her dose of warfarin was suspended and she was given 4 units of fresh frozen plasma as well as 10 mg of i.v. vitamin K. She was discharged home with an INR normalized to 1.3 and cessation of her rectal bleeding. At discharge, she was not restarted on warfarin, nor was any bridging therapy used. The patient returned to the Emergency Department a week later for worsening pain and bluish discoloration of her bilateral lower extremities. An ultrasound (US) examination showed that she had developed bilateral PCD, after INR reversal. Why Should an Emergency Physician Be Aware of This? Emergency physicians commonly care for patients who present with acute DVT or treat patients on anticoagulant therapy who require cessation of medications or administration of prothrombotic agents to reverse bleeding. Cases of extensive clot burden leading to PCD have been reported in the literature, however, reports of bilateral PCD secondary to cessation of warfarin have been scarce. PCD should be considered carefully as one of the complications in warfarin reversal, as it requires immediate attention and surgical intervention to prevent limb loss. |
| Databáze: | OpenAIRE |
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