High diagnostic accuracy for lymph node metastasis of oral squamous cell carcinoma using PET/CT with a silicon photomultiplier

Autor:	Ikuho Kojima, Kentaro Takanami, Takenori Ogawa, Kenichiro Ishikawa, Yohei Morishita, Ryo Ishii, Akira Ohkoshi, Ayako Nakanome, Hayato Odagiri, Masahiro Iikubo
Rok vydání:	2022
Předmět:	Head and Neck Neoplasms Squamous Cell Carcinoma of Head and Neck Lymphatic Metastasis Positron Emission Tomography Computed Tomography Carcinoma Squamous Cell Humans Mouth Neoplasms Radiology Nuclear Medicine and imaging Dentistry (miscellaneous) Retrospective Studies
Zdroj:	Oral Radiology. 38:540-549
ISSN:	1613-9674 0911-6028
DOI:	10.1007/s11282-022-00588-0
Popis:	The higher sensitivity of the new-generation positron emission tomography/computed tomography (PET/CT) with silicon photomultiplier (SiPM) may increase false-positive rates in detecting metastatic lymph nodes (LNs). This study aimed to clarify the usefulness of the SiPM PET scanner in diagnosing LN metastasis of oral squamous cell carcinoma (SCC).We retrospectively reviewed consecutive F-18 fluorodeoxyglucose PET/CT images of 39 SCC patients using SiPM PET and 31 SCC patients using non-SiPM PET. We measured the maximum standardized uptake value (SUVThe sensitivity and specificity of SiPM PET were 86.2% and 95.6%, respectively (cut-off SUVSiPM PET had higher diagnostic accuracy for LN metastasis of oral SCC than non-SiPM PET, even for small LN metastasis without increasing false-positives.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea12666d59b4b3d4a4de4ee80e368e11 https://doi.org/10.1007/s11282-022-00588-0 Zobrazit plný text záznamu Full text from SpringerLink