Plasmodium yoelii and Plasmodium vinckei: The effects of nonspecific immunostimulation on murine malaria
| Autor: | Barrie J. Cottrell, John H.L. Playfair, Brian De Sousa |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Lipopolysaccharides
Male Plasmodium Erythrocytes Reticulocytes Lipopolysaccharide Plasmodium berghei Plasmodium vinckei Immunology Babesia Microbiology Mice chemistry.chemical_compound Immune system Adjuvants Immunologic parasitic diseases Concanavalin A Escherichia coli Animals Propionibacterium acnes Diethylstilbestrol Innate immune system biology Polysaccharides Bacterial Lymphokine General Medicine biology.organism_classification Virology Malaria Blood Infectious Diseases chemistry Poly A-U Female Parasitology Injections Intraperitoneal Plasmodium yoelii |
| Zdroj: | Experimental Parasitology. 43:45-53 |
| ISSN: | 0014-4894 |
| DOI: | 10.1016/0014-4894(77)90006-6 |
| Popis: | Nonspecific stimulation of the immune system in mice and its effects on Plasmodium yoelii and Plasmodium vinckei infections were studied using the agents: Corynebacterium parvum, Concanavalin-A, lipopolysaccharide (LPS), a polymer of adenine and uridine units [poly(A:U)], and diethylstilbestrol (DES). C. parvum proved to be the best stimulant against both P. yoelii and P. vinckei. Poly(A:U) on the other hand had no or little effect on either parasite. Results obtained from DES-treated mice suggested that the reticuloendothelial system may differentially handle parasites inhabiting the mature red blood cells in contrast to those within the reticulocytes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|