The epidemiology of cytomegaloviral infection in women attending a sexually transmitted disease clinic
| Autor: | E. R. Alexander, Paul J. Wiesner, King K. Holmes, H. Hunter Handsfield, Laura T. Gutman, Wentworth Bb, Susan H. Chandler |
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| Rok vydání: | 1985 |
| Předmět: |
Sexually transmitted disease
Adult medicine.medical_specialty Sexual Behavior Congenital cytomegalovirus infection Sexually Transmitted Diseases Cytomegalovirus Cervix Uteri Logistic regression Antibodies Viral Internal medicine Epidemiology medicine Immunology and Allergy Humans business.industry Complement Fixation Tests Antibody titer Age Factors virus diseases Sexually transmitted disease clinic Chlamydia Infections medicine.disease Sexual intercourse Infectious Diseases Cytomegaloviral Infection Socioeconomic Factors Immunology Cytomegalovirus Infections Regression Analysis Female business |
| Zdroj: | The Journal of infectious diseases. 152(3) |
| ISSN: | 0022-1899 |
| Popis: | To test the hypothesis that cytomegalovirus (CMV) is sexually transmitted, we examined the association of CMV infection with indices of sexual activity in 347 women attending a sexually transmitted disease (STD) clinic. Stepwise multivariate logistic regression analysis showed that seropositivity to CMV (complement-fixation antibody titer, greater than or equal to 1:8) was most closely associated with number of sex partners in the subjects' lifetime (P less than .0001), young age at first sexual intercourse (P = .0002), and nonwhite race (P = .0007). Among seropositive women, cervical shedding of CMV was most strongly associated with younger age (P = .0001) and the presence of cervical chlamydial infection (P = .016). Among 84 seronegative women followed up for a mean of 18.4 weeks, 11 (13%) developed primary CMV infections, an annual incidence of 37%. Sexual contact seems to be an important mode of acquisition of CMV in some young women. |
| Databáze: | OpenAIRE |
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