Prospective Study on Efficacy and Tolerability of Solvent/ Detergent-Treated Plasma in Intensive Care Unit Patients
| Autor: | G.A. Walz, W. Thürigen, E. Larbig, P. Hellstern, K. Oberfrank |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Male
medicine.medical_specialty Octoxynol Detergents Blood Loss Surgical Blood Pressure Blood volume Fibrinogen Antiviral Agents Polyethylene Glycols law.invention Plasma Postoperative Complications Heart Rate law medicine Humans Immunology and Allergy Prospective Studies Aged Prothrombin time Disseminated intravascular coagulation Hemostasis medicine.diagnostic_test business.industry Antithrombin Hematology Disseminated Intravascular Coagulation Middle Aged medicine.disease Intensive care unit Organophosphates Surgery Intensive Care Units Anesthesia Solvents Female business medicine.drug Partial thromboplastin time |
| Zdroj: | Transfusion Medicine and Hemotherapy. 20:16-18 |
| ISSN: | 1660-3818 1660-3796 |
| DOI: | 10.1159/000222917 |
| Popis: | Thirty patients who were postoperatively admitted to the intensive care unit had to be treated because of disseminated intravascular coagulation and/or coagulopathy resulting from blood volume dilution or loss. These patients received a single dose of solvent/detergent-treated plasma (Octaplas®). No other blood products were administered 6 h prior to and 1 h after completion of the plasma infusion. Coagulation analyses were performed before and 10-60 min after plasma administration. Prothrombin time, fibrinogen, antithrombin III, and systolic blood pressure improved significantly due to plasma therapy. Activated partial thromboplastin time and platelet count also improved, but the differences were not significant. During the observation period, no side effects occurred. The subjectively assessed hemostatic effect was good. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|