Asthma in the Real-World: The Relevance of Gender
| Autor: | Giorgio Ciprandi, Stefano Levra, Andrea Elio Sprio, Fabio Gallo, Fabio Luigi Massimo Ricciardolo, Vitina Carriero, Francesca Bertolini |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Immunology Physical examination Severity of Illness Index Severity 03 medical and health sciences FEV1/FVC ratio Age Distribution Sex Factors 0302 clinical medicine Internal medicine Asthma control Control medicine Humans Immunology and Allergy Asthmatic patient 030223 otorhinolaryngology Lung Asthma Gender Lung function Real-world setting Type 2 inflammation medicine.diagnostic_test business.industry Smoking General Medicine Asthma clinic Middle Aged medicine.disease Respiratory Function Tests Cross-Sectional Studies 030228 respiratory system Exhaled nitric oxide Female business |
| Zdroj: | International Archives of Allergy and Immunology. 181:462-466 |
| ISSN: | 1423-0097 1018-2438 |
| DOI: | 10.1159/000506808 |
| Popis: | Background: The possible gender impact on asthma arouses current and outstanding interest, but few studies addressed this issue in the real-world setting. Objective: This cross-sectional study tested the hypothesis of a potential difference between asthmatic males and females in a real-life setting, such as a third-level asthma clinic. Methods: A total of 499 asthmatic outpatients (301 females and 198 males, mean age 58.25 years) were consecutively visited. The visit included history, asthma control, and severity grade, physical examination, lung function, fractional exhaled nitric oxide assessment, and blood sample for biomarkers. Results: There were more females than males (about 3 of 5). Asthmatic females smoked less (p < 0.0001) than males and had higher FEV1 (p = 0.0022) and FVC (p = 0.0004) values than asthmatic males. Conclusions: Gender difference was associated with smoking and lung function impairment; thus, this issue should be carefully considered in asthmatic patients in daily clinical practice. |
| Databáze: | OpenAIRE |
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