Clinical characteristics of familial schizophrenia
| Autor: | F. Yang, Tiebang Liu, Mingyuan Zhang, Chunxia Wang, Xilin Wang, Fu-jun Jia, Zhenyu Hu, Jian Hu, Qi-Yi Mei, Jingping Zhao, Xiufeng Xu, Xueli Sun, Xiangqun Wang, Qingwei Li, Xiangyu Xiong, Hui-Chun Li, Xiaoxin Yang, Ning Zhang, Jinbei Zhang, Hua-qing Meng, Xinjun Zhang, Na Liu, Qingrong Tan, Hui Zhou, Zuoming Chen, Chunqing Peng, Zheng Lu, Gaohua Wang, Gang Wang, Xuefeng Jiang, Jing Li, Bing Feng, Lingyang Du |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Demographics business.industry Alcohol dependence Mental disease General Medicine medicine.disease 030227 psychiatry Hospitalization 03 medical and health sciences Psychiatry and Mental health 0302 clinical medicine Multicenter study Psychotic Disorders Schizophrenia Risk Factors Medicine Humans Multiple logistic regression analysis Family history business Psychiatry 030217 neurology & neurosurgery Physical illness |
| Zdroj: | Asia-Pacific psychiatry : official journal of the Pacific Rim College of PsychiatristsREFERENCES. 13(2) |
| ISSN: | 1758-5872 |
| Popis: | Introduction A family history of psychiatric disorders is one of the strongest risk factors for schizophrenia. The characteristics of patients with a family history of psychiatric disorders have not been systematically evaluated. Methods This multicenter study (26 centers, 2425 cases) was performed in a Chinese population to examine the sociodemographic and clinical characteristics of schizophrenia patients with a family history of psychotic disorders in comparison with those of patients with sporadic schizophrenia. Results Nineteen percent of patients had a family history of mental disease. Multiple logistic regression analysis revealed that ≥4 hospitalizations (OR = 1.78, P = .004), tobacco dependence (OR = 1.48, P = .006), alcohol dependence (OR = 1.74, P = .013), and physical illness (OR = 1.89, P = .001) were independently and significantly associated with a family history of mental disease. Conclusion Patients with a family history of mental disorders present different demographics and clinical features than patients without a family history of psychiatric disorders. |
| Databáze: | OpenAIRE |
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