Diels–Alder reactions of myrcene using intensified continuous-flow reactors
| Autor: | John Tsanaktsidis, Christian H. Hornung, Thomas M. Kohl, Miguel Á Álvarez-Diéguez |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
flow chemistry
surfactant 010402 general chemistry 01 natural sciences Full Research Paper Adduct lcsh:QD241-441 chemistry.chemical_compound Pulmonary surfactant lcsh:Organic chemistry renewable feedstock Diels alder Organic chemistry lcsh:Science Acrylic acid continuous processing 010405 organic chemistry Chemistry Continuous flow Organic Chemistry 0104 chemical sciences Volume (thermodynamics) Myrcene Batch processing lcsh:Q |
| Zdroj: | Beilstein Journal of Organic Chemistry, Vol 13, Iss 1, Pp 120-126 (2017) Beilstein Journal of Organic Chemistry |
| ISSN: | 1860-5397 |
| Popis: | This work describes the Diels–Alder reaction of the naturally occurring substituted butadiene, myrcene, with a range of different naturally occurring and synthetic dienophiles. The synthesis of the Diels–Alder adduct from myrcene and acrylic acid, containing surfactant properties, was scaled-up in a plate-type continuous-flow reactor with a volume of 105 mL to a throughput of 2.79 kg of the final product per day. This continuous-flow approach provides a facile alternative scale-up route to conventional batch processing, and it helps to intensify the synthesis protocol by applying higher reaction temperatures and shorter reaction times. |
| Databáze: | OpenAIRE |
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