Contemporary assessment of the correlation between Bosniak classification and histological characteristics of surgically removed atypical renal cysts (UroCCR-12 study)
| Autor: | Yves Allory, Gaëlle Fromont-Hankard, François Cornelis, Jean-Christophe Bernhard, Mokrane Yacoub, Sofiane Béjar, Véronique Lindner, Nathalie Rioux-Leclercq, Laurent Daniel, Nicolas Grenier, Arnaud Mejean, Karim Bensalah, Virginie Verkarre, Pierre Bigot, Zine-Eddine Khene, Cosmina Nedelcu, François-Xavier Nouhaud, Jean-Michel Correas, François Audenet, G. Fraisse, S. Bergerat, Herve Lang |
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| Přispěvatelé: | Institut de recherche en santé, environnement et travail (Irset), Université d'Angers (UA)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Université d'Angers (UA)-Université de Rennes (UR)-École des Hautes Études en Santé Publique [EHESP] (EHESP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ) |
| Rok vydání: | 2018 |
| Předmět: |
Male
Nephrology medicine.medical_specialty Histology Urology 030232 urology & nephrology Bosniak classification [SDV.CAN]Life Sciences [q-bio]/Cancer Renal cysts 03 medical and health sciences 0302 clinical medicine Renal cell carcinoma Internal medicine medicine Humans Cyst Stage (cooking) Carcinoma Renal Cell Computed tomography Pathological ComputingMilieux_MISCELLANEOUS Aged Neoplasm Staging Retrospective Studies Cysts business.industry Kidney Diseases Cystic Middle Aged Prognosis medicine.disease Kidney Neoplasms 3. Good health Clear cell renal cell carcinoma 030220 oncology & carcinogenesis Female Low malignant potential Radiology Neoplasm Recurrence Local Tomography X-Ray Computed business Kidney cancer |
| Zdroj: | World Journal of Urology World Journal of Urology, Springer Verlag, 2018, 36 (10), pp.1643-1649. ⟨10.1007/s00345-018-2307-6⟩ World Journal of Urology, 2018, 36 (10), pp.1643-1649. ⟨10.1007/s00345-018-2307-6⟩ |
| ISSN: | 1433-8726 0724-4983 |
| DOI: | 10.1007/s00345-018-2307-6 |
| Popis: | To evaluate and compare pathological characteristics of renal cysts Bosniak IIF, III and IV in light of recent histological classification. The French research network for kidney cancer UroCCR conducted a multicentre study on patients treated surgically for a renal cyst between 2007 and 2016. Independent radiological and centralized pathological reviews were performed for every patient. Pathological characteristics were compared to the Bosniak classification. Of a total 216 patients included, 175 (81.0%) tumours (90.9% of Bosniak IV, 69.8% of Bosniak III) were malignant or had a low malignant potential, with 60% of clear cell renal cell carcinoma (CCRCC), 24% of papillary RCC (PRCC) and 6.9% of multilocular cystic renal tumour of low malignant potential (MCRTLMP). Malignancies were mostly of low pT stage (86.4% of pT1–2), and low ISUP grade (68.0% of 1–2). Bosniak III cysts had a lower rate of CCRCC (46.7 vs. 67.3%), higher rate of PRCC (30 vs. 20.9%) and MCRTLMP (18.3 vs. 0.9%) compared to Bosniak IV (p |
| Databáze: | OpenAIRE |
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