| Autor: |
Gabriel M. C. Barros, Dionísio D. A. Carvalho, Agnaldo S. Cruz, Ellen K. L. Morais, Ana Isabela L. Sales-Moioli, Talita K. B. Pinto, Melise C. D. Almeida, Ignacio Sanchez-Gendriz, Felipe Fernandes, Ingridy M. P. Barbalho, João P. Q. Santos, Jorge M. O. Henriques, César A. D. Teixeira, Paulo Gil, Lúcio Gama, Angélica E. Miranda, Karilany D. Coutinho, Leonardo J. Galvão-Lima, Ricardo A. M. Valentim |
| Přispěvatelé: |
DEE - Departamento de Engenharia Electrotécnica e de Computadores |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
International Journal of Environmental Research and Public Health; Volume 19; Issue 23; Pages: 16206 |
| ISSN: |
1660-4601 |
| Popis: |
54/2017). Publisher Copyright: © 2022 by the authors. The improvement of laboratory diagnosis is a critical step for the reduction of syphilis cases around the world. In this paper, we present the development of an impedance-based method for detecting T. pallidum antigens and antibodies as an auxiliary tool for syphilis laboratory diagnosis. We evaluate the voltammetric signal obtained after incubation in carbon or gold nanoparticle-modified carbon electrodes in the presence or absence of Poly-L-Lysine. Our results indicate that the signal obtained from the electrodes was sufficient to distinguish between infected and non-infected samples immediately (T0′) or 15 min (T15′) after incubation, indicating its potential use as a point-of-care method as a screening strategy. publishersversion published |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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