Salivary Hormones and Quality of Life in Female Postmenopausal Burning Mouth Patients—A Pilot Case-Control Study
Autor: | Valentina Vidranski, Ivana Todorić-Laidlaw, Danica Vidović-Juras, Božana Lončar-Brzak, Ivana Škrinjar, Ana Andabak-Rogulj, Dragana Gabrić |
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Jazyk: | angličtina |
Rok vydání: | 2020 |
Předmět: |
burning mouth syndrome
BIOMEDICINA I ZDRAVSTVO. Dentalna medicina Saliva salivary hormones quality of life Dehydroepiandrosterone Physiology Article 03 medical and health sciences 0302 clinical medicine Quality of life Medicine BIOMEDICINE AND HEALTHCARE. Dental Medicine Burning mouth General Dentistry Morning business.industry Case-control study 030206 dentistry Burning mouth syndrome lcsh:RK1-715 lcsh:Dentistry medicine.symptom business 030217 neurology & neurosurgery Hormone |
Zdroj: | Dentistry Journal, Vol 8, Iss 111, p 111 (2020) Dentistry Journal Volume 8 Issue 4 |
ISSN: | 2304-6767 |
Popis: | The objective of our study was to investigate salivary levels of estradiol, progesterone and dehydroepiandrosterone (DHEA), and quality of life, in female postmenopausal women with burning mouth syndrome. The study included new patients diagnosed with burning mouth syndrome and excluded local and systemic causes. Unstimulated saliva samples were taken in the morning from 9 AM and 11 AM and immediately frozen for hormone analysis. The patients filled out a self-perceived quality of life questionnaire Oral Health Impact Profile-14 and determined the intensity of mucosal symptoms according to the visual-analog scale grading 0 to 10. A total of 40 patients were included. The study group had significantly lower levels of salivary estradiol. No difference was observed in levels of progesterone and DHEA between the groups. The levels of salivary hormones did not exhibit a significant correlation according to the Spearman correlation test with a self-perceived quality of life questionnaire (OHIP-14) in the study group or in the control group. Further research on a larger number of patients is needed to verify these results. This information might help to enable more precise and efficient treatment. |
Databáze: | OpenAIRE |
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