Survival after repeat hepatic resection for recurrent colorectal hepatic metastases
| Autor: | Alexander Doolas, David L. Roseman, Lee Jenkins, Keith W. Millikan, Steven D. Bines |
|---|---|
| Rok vydání: | 1996 |
| Předmět: |
Adult
Male Reoperation medicine.medical_specialty Hepatic resection Colorectal cancer Blood Loss Surgical Retrospective data Resection Blood loss Recurrence Recurrent disease Medicine Humans Aged Retrospective Studies business.industry Liver Neoplasms Repeat resection Middle Aged medicine.disease Survival Analysis Surgery Population study Female business Colorectal Neoplasms Follow-Up Studies |
| Zdroj: | Surgery. 120(4) |
| ISSN: | 0039-6060 |
| Popis: | Background. This is a retrospective clinical study done to examine survival of patients undergoing repeat hepatic resection for recurrent colorectal hepatic metastases. Methods. The records of 131 patients undergoing hepatic resection for metastatic colorectal cancer were reviewed. Curative resection was performed in 107 of these patients. Thirty-one experienced recurrences confined to the liver. Thirteen (13 of 107, 12%) of them underwent resection and make up the study population. Results. The eight men (62%) and five women (38%) had a median age of 60 years (range, 32 to 75 years). In 30% of patients recurrence developed near the original resection site. In 70% the recurrences were remote from the original site. The patients underwent a total of six wedge resections, two left lateral segmentectomies, three right lobectomies, and two trisegmentectomies. Average blood loss was 2995 cc; average hospital stay was 17.2 days. Morbidity was 23% (3 of 13); mortality was 8% (1 of 13). Four patients died of recurrent disease, with a mean disease-free survival of 9.7 months (median, 7.5 months; range, 3 to 21 months) and mean total survival of 39 months (median, 24 months; range, 8 to 99 months). One of these patients had a second recurrence resected at month 21 and lived an additional 78 months. Seven patients were alive with no evidence of disease, with a mean follow-up time of 34.9 months (median, 14 months; range, 1 to 186 months). Actual 5-year survival was 23% (3 of 13). Actual disease-free 5-year survival was 15% (2 of 13). Conclusions. In properly selected patients morbidity, mortality, and survival after repeat resection are similar to those after initial resection. |
| Databáze: | OpenAIRE |
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