Calcium, Barium and Strontium apatites: A new generation of catalysts in the Biginelli reaction
| Autor: | Kaia Tõnsuaadu, Jalel Lachheb, Michel Gruselle, Birgit Maaten, Sana Ben Moussa, Tõnis Kanger, Béchir Badraoui, Kadri Kriis |
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| Přispěvatelé: | Université de Monastir - University of Monastir (UM), Institut Parisien de Chimie Moléculaire (IPCM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Tallinn University of Technology (TTÜ), Institut de Chimie du CNRS (INC)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Strontium
010405 organic chemistry Magnesium [CHIM.ORGA]Chemical Sciences/Organic chemistry Organic Chemistry Biginelli reaction Inorganic chemistry chemistry.chemical_element Barium Zinc [CHIM.CATA]Chemical Sciences/Catalysis 010402 general chemistry Modified hydroxyapatite 01 natural sciences Biochemistry Catalysis 0104 chemical sciences Hydroxyapatite chemistry Drug Discovery Hydroxyapatites Palladium |
| Zdroj: | Tetrahedron Tetrahedron, Elsevier, 2017, 73 (46), pp.6542-6548. ⟨10.1016/j.tet.2017.09.051⟩ Tetrahedron, 2017, 73 (46), pp.6542-6548. ⟨10.1016/j.tet.2017.09.051⟩ |
| ISSN: | 0040-4020 |
| DOI: | 10.1016/j.tet.2017.09.051⟩ |
| Popis: | International audience; We describe herein the use of Calcium, Barium and Strontium hydroxyapatites (CaHAp, BaHAp and SrHAp) as well as CaHAp containing Magnesium, Copper, Zinc and Palladium (MgHAp, CuHAp, ZnHAp and PdHAp) as catalysts in the Biginelli reaction. The efficiency of CaHAp and SrHAp is very low, leading to the expected 3,4-dihydropyrimidin-2(1H)-one in poor yields. Mixed Ba 5 Sr 5 HAp and Ba 10 HAp show interesting catalytic properties, especially Ba 10 HAp leading to pure isolated reaction products in good yields. The use of modified CaHAp seems to be of interest in regard to the yield obtained. Nevertheless the release of Mg, Cu, Zn and Pd ions in the solution during the catalytic process makes the use of such modified apatites less effective. |
| Databáze: | OpenAIRE |
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