Percutaneous CT-Guided Cryoablation of the Celiac Plexus: A Retrospective Cohort Comparison with Ethanol
| Autor: | Sajal Patel, Howard B. Fleishon, Keywan Behbahani, J. David Prologo, Jason W. Mitchell, Aron Chary |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Diarrhea Male medicine.medical_specialty Time Factors Nausea medicine.medical_treatment Celiac plexus Celiac Plexus Radiography Interventional Cryosurgery 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Risk Factors medicine Humans Radiology Nuclear Medicine and imaging Neurolysis Aged Pain Measurement Retrospective Studies Ethanol business.industry Incidence Incidence (epidemiology) Cryoablation Retrospective cohort study Middle Aged Abdominal Pain Pain Intractable Surgery Treatment Outcome medicine.anatomical_structure 030220 oncology & carcinogenesis Vomiting Female medicine.symptom Tomography X-Ray Computed Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of Vascular and Interventional Radiology. 31:1216-1220 |
| ISSN: | 1051-0443 |
| Popis: | Purpose To retrospectively analyze and compare the incidence of diarrhea in patients who underwent cryoablation of the celiac plexus for intractable abdominal pain versus ethanol therapy over a 5-year period. Materials and Methods From June 2014 to August 2019, 83 patients were identified who underwent neurolysis of the celiac plexus for management of intractable abdominal pain by using either cryoablation (n = 39 [59% female; age range, 36–79 years old [average, 60 ± 11 years old]) or alcohol (n = 44 [48% female; age range, 29–76 years old [average, 60 ± 12 years old]). Pain scores and reports of procedure-related complications or side effects, with special attention to diarrhea and/or other gastrointestinal symptoms, were collected from follow-up visits at 1 week, 1 month, and 3 months post-intervention and were compared between groups. Results The mean time of follow-up was 17.7 days. Four patients who underwent cryoablation developed gastrointestinal symptoms consisting of 2 cases of nausea and vomiting and 2 cases of diarrhea (5.1%). Twelve patients who underwent ethanol ablation developed gastrointestinal symptoms, including 1 case of nausea, 3 cases of vomiting, and 9 cases of diarrhea (20.5%). There was a significantly higher incidence of both diarrhea (chi-squared likelihood ratio, P = .03) and overall gastrointestinal symptoms (chi-squared likelihood ratio, P = .04) in the ethanol group than in the cryoablation group. Conclusions Cryoablation of the celiac plexus may provide a new treatment option for intractable abdominal pain, and it appears to have a lower incidence of diarrhea and fewer gastrointestinal side effects than ablation using ethanol. |
| Databáze: | OpenAIRE |
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