Things that could be Mycoplasma pneumoniae
| Autor: | Ruben C A de Groot, Wendy W. J. Unger, Annemarie M. C. van Rossum, Patrick M. Meyer Sauteur |
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| Přispěvatelé: | Pediatrics, University of Zurich, van Rossum, Annemarie M C |
| Rok vydání: | 2017 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Mycoplasma pneumoniae 610 Medicine & health medicine.disease_cause Asymptomatic 2726 Microbiology (medical) Serology Pathogenesis 03 medical and health sciences 0302 clinical medicine Immune system Pneumonia Mycoplasma medicine Humans Immunologic Factors 030212 general & internal medicine Guillain-Barre syndrome Diagnostic Tests Routine business.industry Disease Management 2725 Infectious Diseases medicine.disease Anti-Bacterial Agents 030104 developmental biology Infectious Diseases 10036 Medical Clinic Infectious arthritis Immunology Macrolides Immunomodulation Therapy medicine.symptom business |
| Zdroj: | Journal of Infection, 74, S95-S100. W.B. Saunders |
| ISSN: | 0163-4453 |
| DOI: | 10.1016/s0163-4453(17)30198-6 |
| Popis: | M. pneumoniae infection gives rise to a wide variety of manifestations. The pathogenesis of secondary manifestations is not always known. Some depend on the direct invasion of M. pneumoniae and others on the indirect effect of M. pneumoniae through pathological immune responses, for instance autoreactive antibodies in Guillain-Barré Syndrome. Diagnosis remains challenging with currently available diagnostic tests, because they do not demonstrate a causal relation due to M. pneumoniae asymptomatic carriage or previous infection. The mainstay of treatment is macrolide antibiotics, but the role of additional immunomodulation therapy is unclear. Knowledge of the pathogenesis of the different manifestations should guide strategies for diagnosis and treatment. |
| Databáze: | OpenAIRE |
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