Retrieval procedure for time-resolved near-infrared tissue spectroscopy based on the optimal estimation method
| Autor: | Giovanni Zaccanti, Samuele Del Bianco, Fabrizio Martelli |
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| Rok vydání: | 2012 |
| Předmět: |
Accuracy and precision
Mathematical optimization Time Factors Diffusion equation Infrared Rays Statistics as Topic Monte Carlo method 01 natural sciences 030218 nuclear medicine & medical imaging Optimal estimation method 010309 optics 03 medical and health sciences 0302 clinical medicine 0103 physical sciences Radiative transfer Radiology Nuclear Medicine and imaging Mathematics Retrieval Radiological and Ultrasound Technology Optimal estimation Spectrum Analysis Computer Science::Information Retrieval Inverse problem Molecular Imaging Nonlinear system Time-resolved near-infrared tissue spectroscopy A priori and a posteriori Monte Carlo Method Algorithm |
| Zdroj: | Physics in Medicine and Biology Physics in medicine and biology 57 (2012): 2915–2929. doi:10.1088/0031-9155/57/10/2915 info:cnr-pdr/source/autori:Martelli F; Del Bianco S; Zaccanti G/titolo:Retrieval procedure for time-resolved near-infrared tissue spectroscopy based on the optimal estimation method/doi:10.1088%2F0031-9155%2F57%2F10%2F2915/rivista:Physics in medicine and biology (Print)/anno:2012/pagina_da:2915/pagina_a:2929/intervallo_pagine:2915–2929/volume:57 Physics in Medicine and Biology; Vol 57 |
| ISSN: | 1361-6560 0031-9155 |
| DOI: | 10.1088/0031-9155/57/10/2915 |
| Popis: | We propose the use of a retrieval procedure for time-resolved near-infrared tissue spectroscopy based on the 'optimal estimation' method. The aim of this retrieval method is to obtain an improved estimate of the target parameters compared with standard nonlinear least-squares routines, since the inverse problem dedicated to retrieve the optical properties of tissue is ill posed. A priori information on target and forward model parameters is used, so that a larger number of target parameters can be retrieved, and/or a better accuracy and precision can be achieved on the retrieved target parameters. The procedure has been tested on time-resolved simulated experiments generated, using solutions of the diffusion equation and with solutions of the radiative transfer equation reconstructed with Monte Carlo simulations. The results obtained show that, by using a priori information on target parameters, we have a smaller difference between retrieved values and true values, and lower retrieved error bars. Similarly, a more correct estimate of the errors of the forward model parameters improves the retrieval of the target parameters. |
| Databáze: | OpenAIRE |
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