Neurologic disease in human immunodeficiency virus-infected drug abusers
| Autor: | Germaine Jacquette, Jay Dobkin, Renée Malouf, John C. M. Brust |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Pediatrics medicine.medical_specialty Drug abuser Human immunodeficiency virus (HIV) AIDS-related complex medicine.disease_cause Arts and Humanities (miscellaneous) Acquired immunodeficiency syndrome (AIDS) AIDS-Related Complex Immunopathology Epidemiology medicine Humans Substance Abuse Intravenous Acquired Immunodeficiency Syndrome Brain Diseases business.industry Middle Aged medicine.disease Substance abuse Radiography Immunology Female Neurology (clinical) Viral disease Nervous System Diseases business |
| Zdroj: | Archives of neurology. 47(9) |
| ISSN: | 0003-9942 |
| Popis: | • Previous studies of human immunodeficiency virus-related neurologic disease have been either retrospective or have included mostly homosexual patients. We sought to determine (1) the true prevalence of neurologic abnormalities in patients with acquired immunodeficiency syndrome or lymphadenopathy acquired immunodeficiency-related complex, and (2) whether differences in prevalence or type of neurological abnormality exist between parenteral drug abusers and non-parenteral drug abusers. We prospectively evaluated 190 adult inpatients with either acquired immunodeficiency syndrome (129) or lymphadenopathy acquired immunodeficiency-related complex (61); 151 (80%) were parenteral drug abusers, and 172 patients (91%) had neurologic symptoms or signs. There was no significant difference in prevalence of neurologic disease between parenteral drug abusers and non-parenteral drug abusers, or between patients with acquired immunodeficiency syndrome and those with lymphadenopathy acquired immunodeficiencyrelated complex. The prevalence of neurologic symptoms in these patients with lymphadenopathy acquired immunodeficiency-related complex and acquired immunodeficiency syndrome is the highest reported to date and appears to reflect the prospective nature of the study. |
| Databáze: | OpenAIRE |
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