Impairment of left atrial function and cryptogenic stroke: Potential insights in the pathophysiology of stroke in the young
| Autor: | Kazuaki Negishi, Maria do Carmo Pereira Nunes, Aditya Bhat, Timothy C. Tan, Gary C.H. Gan, C. Raina MacIntyre, Shaun Khanna, Henry H Chen, Lina Lee |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
lcsh:Diseases of the circulatory (Cardiovascular) system
medicine.medical_specialty TAPSE Tricuspid annular plane systolic excursion Population LVEDD Left ventricular end diastolic diameter Disease 030204 cardiovascular system & hematology LAEF Left atrial ejection fraction 03 medical and health sciences 0302 clinical medicine LA Left atrial Interquartile range Internal medicine medicine 030212 general & internal medicine cardiovascular diseases education Stroke Left atrial function RVSP Right ventricular systolic pressure LA GLS Left atrial global longitudinal strain education.field_of_study Original Paper Ejection fraction LVESD Left ventricular end systolic diameter business.industry RA Right atrial RV Right ventricle LV GLS Left ventricular global longitudinal strain Atrial fibrillation medicine.disease Pathophysiology LVEF Left ventricular ejection fraction lcsh:RC666-701 Cardiology Etiology cardiovascular system Cardiology and Cardiovascular Medicine business |
| Zdroj: | International Journal of Cardiology. Heart & Vasculature International Journal of Cardiology: Heart & Vasculature, Vol 26, Iss, Pp-(2020) |
| ISSN: | 2352-9067 |
| Popis: | Highlights • Young patients with cryptogenic strokes have preserved left atrial size. • Left atrial dysfunction is present in young patients with cryptogenic stroke. • Left atrial strain is a discriminator of atrial dysfunction in cryptogenic stroke. • Young paroxysmal AF have abnormal left atrial size and function. Background Stroke is one of the leading causes of morbidity and mortality with a significant percentage classified as cryptogenic. Left atrial (LA) remodelling, a substrate for atrial fibrillation (AF) and stroke development, may play a role in identification of the aetiology of cryptogenic stroke. We aimed to examine LA function to gain mechanistic insights into the pathophysiology of cryptogenic stroke in young patients otherwise at low risk for cardiovascular disease. Methods Patients aged |
| Databáze: | OpenAIRE |
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