Staphylococcus haemolyticus meningitis and bacteremia in an allogenic stem cell transplant patient
| Autor: | Rupert Handy, Richard Doocey, Aliya N. Bryce |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
daptomycin Case Report linezolid Infectious and parasitic diseases RC109-216 medicine.disease_cause chemistry.chemical_compound Internal medicine medicine polycyclic compounds coagulase-negative Staphylococcus immunosuppression biology business.industry meningitis biochemical phenomena metabolism and nutrition biology.organism_classification medicine.disease bacterial infections and mycoses Infectious Diseases chemistry Bacteremia Linezolid Staphylococcus haemolyticus Vancomycin Coagulase Daptomycin business Staphylococcus Meningitis medicine.drug |
| Zdroj: | IDCases, Vol 26, Iss, Pp e01259-(2021) IDCases |
| ISSN: | 2214-2509 |
| Popis: | Staphylococcus haemolyticus is a rare cause of bacterial meningitis and most commonly occurs as a nosocomial infection in patients’ post-neurosurgery. We report a patient post-allogenic stem cell transplant, with no prior history of neurosurgical procedures, who developed S. haemolyticus meningitis and bacteremia following central catheter-related bloodstream infection. The patient failed therapy with vancomycin and daptomycin but was successfully treated with a prolonged course of linezolid. We review the pharmacological management of coagulase negative Staphylococcus (CoNS) meningitis, with a focus on the pharmacokinetic properties of vancomycin, daptomycin and linezolid within the cerebrospinal fluid (CSF). |
| Databáze: | OpenAIRE |
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