Evaluation of short-term efficacy of extraspinal cementoplasty for bone metastasis: A monocenter study of 31 patients
Autor: | Sandra Guignard, Hélene Boussion, Gaëlle Couraud, Florent Eymard, Xavier-Jean Chevalier, A. Hourdille, André-Pierre Gaston, Titien Thuillier |
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Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
medicine.medical_specialty
lcsh:Diseases of the musculoskeletal system lcsh:RC254-282 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Quality of life Pain level medicine Clinical endpoint Adverse effect business.industry Percutaneous Cementoplasty Bone metastasis medicine.disease lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens Pain management Surgery Oncology 030220 oncology & carcinogenesis Cementoplasty lcsh:RC925-935 business Percutaneous cementoplasty Cement leakage Research Article |
Zdroj: | Journal of Bone Oncology, Vol 13, Iss, Pp 136-142 (2018) Journal of Bone Oncology |
ISSN: | 2212-1374 |
Popis: | Objective: To study the effect on pain of per-cutaneous cementoplasty for painful extraspinal bone metastasis. Method: 43 patients with extraspinal bone metastasis were included between April 2006 and October 2014 in this retrospective monocenter study. The primary endpoint was pain level measured on a 0–10 numeric rating scale at week 1 after cementoplasty as compared with pre-cementoplasty. Secondary endpoints were long-term pain level and impact on quality of life and disability. Results: Mean pain score was 4.2 (SD ±3.6) before cementoplasty and 1.09 (SD ±2.4) at week 1 (p = 0.005) (n = 31 patients). At 22 months after cementoplasty, quality of life and disability improved (according to the patient global assessment) for 47.6% and 52.2% of patients (n = 21patients). We did not find a predictor of good response. Cement leakage was the most common adverse event. Conclusion: Percutaneous cementoplasty of extraspinal bone metastasis is a rapidly efficient treatment with few adverse events. Its efficacy persists over time, with a benefit for disability and quality of life. Although this technique is only palliative, it should be considered in this situation. Keywords: Percutaneous cementoplasty, Bone metastasis, Pain management |
Databáze: | OpenAIRE |
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