Myocardial strain pattern progress in patients with Coarctation of the Aorta undergoing aortic stenting
| Autor: | Rodrigo Bellio de Mattos Barretto, Carlos A. C. Pedra, Anderson C. Armstrong, Simone Rolim Fernandes Fontes Pedra, David Le Bihan, Jorge Eduardo Assef, Natalia Freitas de Deus Vale Aragão, Juliana Nicchio Valentim Borgo, Carlos Alberto de Jesus, Tathiane Davoglio |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Adolescent Systole Heart Ventricles Coarctation of the aorta 030204 cardiovascular system & hematology Aortic Coarctation Ventricular Function Left 030218 nuclear medicine & medical imaging Left ventricular mass Ventricular Dysfunction Left 03 medical and health sciences 0302 clinical medicine Internal medicine Humans Medicine Radiology Nuclear Medicine and imaging In patient Subclinical infection Aorta coarctation Ejection fraction Ventricular function business.industry Stroke Volume medicine.disease Echocardiography Myocardial strain Cardiology Cardiology and Cardiovascular Medicine business |
| Zdroj: | Echocardiography. 38:64-71 |
| ISSN: | 1540-8175 0742-2822 |
| DOI: | 10.1111/echo.14937 |
| Popis: | BACKGROUND AND AIM Ventricular function evaluation in coarctation of the aorta (CoA) has become more sophisticated and precise with speckle tracking, revealing subclinical changes. However, CoA stenting treatment effects in on myocardial strain are still controversial. This study aimed to estimate the extent to which changes in left ventricular global longitudinal strain (LV GLS) occur in patients with CoA who undergo stenting. METHODS The study included 21 patients with CoA (median age: 15 years [8-39]) and 21 healthy individuals matched by age and gender. Clinical and echocardiographic evaluations were performed 1 day before, 6 months, and 1 year after stenting. Correlations between LV GLS and arm-leg gradient, isthmus gradient on echocardiogram, age at intervention, left ventricular mass, and ejection fraction were tested. RESULTS Before treatment, patients with CoA had lower LV GLS than the control group (-18.4% ± 1.96 vs -21.5% ± 1.37; P < .01), showing significant increase to -19.4% ± 2.1 at 6 months and -20.7% ± 2.19 at 1 year, P < .001. Only 28.5% (6 patients) had preserved GLS before treatment, improving to 80.9% (17 patients) in 1 year. The only variable correlated with low LV GLS values before treatment was age at intervention (Spearman's index = -0.571; P = .007). CONCLUSION Percutaneous therapy showed significant LV GLS improvement 12 months after aortic stenting. Older patients have lower GLS, suggesting that early intervention may have positive effects on preservation of LV systolic function. |
| Databáze: | OpenAIRE |
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