Concurrent presentation of erythrodermic lichen planus and squamous cell carcinoma: Coincidence or malignant transformation?
| Autor: | Shwetha B Rao, Neema M Ali, Ramesh M Bhat |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
squamous cell carcinoma
Pathology medicine.medical_specialty Population Erythroderma Dermatology Lesion stomatognathic system Biopsy medicine lcsh:Dermatology Neoplastic transformation Bulla (seal) education skin and connective tissue diseases education.field_of_study medicine.diagnostic_test integumentary system business.industry erythroderma lcsh:RL1-803 medicine.disease IJD Focus: Lichen Planus stomatognathic diseases Skin biopsy medicine.symptom business Lichen planus Papulosquamous disorder |
| Zdroj: | Indian Journal of Dermatology, Vol 60, Iss 5, Pp 457-460 (2015) Indian Journal of Dermatology |
| ISSN: | 1998-3611 0019-5154 |
| Popis: | Lichen planus is a common papulosquamous disorder affecting about 1-2% of the population, neoplastic transformation of cutaneous lichen planus lesions occurs very rarely. A 40 year old female patient presented with a 1 year history of developing multiple, itchy, pigmented lesions over both lower legs which gradually spread to involve the whole body. A few tense bullae were seen on the extremities. An erythematous fleshy lesion was seen on the upper aspect of the left buttock. Skin biopsy from a plaque on the right forearm showed features suggestive of lichen planus. Skin biopsy of a bullae showed a sub epidermal bulla filled with a mixed inflammatory infiltrate. Direct immunofluorescence revealed no immunoreactants along the basement membrane zone. A diagnosis of erythrodermic lichen planus with bullous lichen planus was made. Biopsy of fleshy lesion of left buttock revealed a moderately differentiated squamous cell carcinoma. Erythrodermic lichen planus with bullous lesions and secondary squamous cell carcinoma; these occurences in a single patient is extremely rare and has not been previously reported to the best of our knowledge. |
| Databáze: | OpenAIRE |
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