The effect of semen collection location and time to processing on sperm parameters and early IVF/ICSI outcomes
Autor: | Charles L. Bormann, Caitlin R. Sacha, Stylianos Vagios, Karissa C. Hammer, Irene Souter, Victoria W. Fitz |
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Rok vydání: | 2021 |
Předmět: |
Male
0301 basic medicine Time Factors Pregnancy Rate Embryo development 0302 clinical medicine Pregnancy Outcome Assessment Health Care Ambulatory Care Assisted Reproduction Technologies reproductive and urinary physiology Genetics (clinical) Sperm motility media_common 030219 obstetrics & reproductive medicine medicine.diagnostic_test Obstetrics and Gynecology General Medicine Spermatozoa Embryo transfer Semen processing IVF Sperm Motility Female Sperm parameters Adult medicine.medical_specialty media_common.quotation_subject Semen Fertility Fertilization in Vitro Semen analysis Semen collection 03 medical and health sciences Genetics medicine Humans Timing Sperm Injections Intracytoplasmic Retrospective Studies Gynecology urogenital system business.industry COVID-19 Embryo Transfer Sperm Semen Analysis Pregnancy rate Blastocyst 030104 developmental biology Reproductive Medicine Fertilization business Semen Preservation Developmental Biology |
Zdroj: | Journal of Assisted Reproduction and Genetics |
ISSN: | 1573-7330 1058-0468 |
Popis: | Purpose We aimed to assess whether home collection and increased time to semen processing are associated with altered sperm parameters, fertilization rates (FR), day 5 usable quality blastocyst development rates (D5-UQBR), or pregnancy rates (PR) in patients undergoing IVF/ICSI. Methods This was a retrospective cohort study of patients undergoing IVF/ICSI before the coronavirus disease 2019 (COVID-19) pandemic (“clinic” collection, n = 119) and after COVID-19 (“home” collection, n = 125) at an academic fertility practice. Home collection occurred within 2 h of semen processing. Patient sperm parameters, FR (#2PN/MII), D5-UQBR (# transferable and freezable quality blastocysts/# 2PN), and PR in fresh transfer cycles were compared between clinic and home groups with t-tests. The association between time to processing on outcomes was assessed with regression modeling, controlling for potential confounders. Results Mean male age was 37.9 years in the clinic group and 37.2 years in the home group (p = 0.380). On average, men were abstinent for 3.0 days (SD 1.7) in the clinic group and 4.1 days (SD 5.4) in the home group (p = 0.028). Mean time to semen processing was 35.7 min (SD 9.4) in the clinic group and 82.6 min (SD 33.8) in the home group (p < 0.001). There was no association between collection location and increased time to processing on sperm motility, total motile count, FR, D5-UQBR, or PR. Conclusions Our data suggest that increased time to processing up to 2 h with home semen collection does not negatively impact sperm parameters or early IVF/ICSI outcomes. |
Databáze: | OpenAIRE |
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