The effect of semen collection location and time to processing on sperm parameters and early IVF/ICSI outcomes

Autor: Charles L. Bormann, Caitlin R. Sacha, Stylianos Vagios, Karissa C. Hammer, Irene Souter, Victoria W. Fitz
Rok vydání: 2021
Předmět:
Male
0301 basic medicine
Time Factors
Pregnancy Rate
Embryo development
0302 clinical medicine
Pregnancy
Outcome Assessment
Health Care
Ambulatory Care
Assisted Reproduction Technologies
reproductive and urinary physiology
Genetics (clinical)
Sperm motility
media_common
030219 obstetrics & reproductive medicine
medicine.diagnostic_test
Obstetrics and Gynecology
General Medicine
Spermatozoa
Embryo transfer
Semen processing
IVF
Sperm Motility
Female
Sperm parameters
Adult
medicine.medical_specialty
media_common.quotation_subject
Semen
Fertility
Fertilization in Vitro
Semen analysis
Semen collection
03 medical and health sciences
Genetics
medicine
Humans
Timing
Sperm Injections
Intracytoplasmic
Retrospective Studies
Gynecology
urogenital system
business.industry
COVID-19
Embryo Transfer
Sperm
Semen Analysis
Pregnancy rate
Blastocyst
030104 developmental biology
Reproductive Medicine
Fertilization
business
Semen Preservation
Developmental Biology
Zdroj: Journal of Assisted Reproduction and Genetics
ISSN: 1573-7330
1058-0468
Popis: Purpose We aimed to assess whether home collection and increased time to semen processing are associated with altered sperm parameters, fertilization rates (FR), day 5 usable quality blastocyst development rates (D5-UQBR), or pregnancy rates (PR) in patients undergoing IVF/ICSI. Methods This was a retrospective cohort study of patients undergoing IVF/ICSI before the coronavirus disease 2019 (COVID-19) pandemic (“clinic” collection, n = 119) and after COVID-19 (“home” collection, n = 125) at an academic fertility practice. Home collection occurred within 2 h of semen processing. Patient sperm parameters, FR (#2PN/MII), D5-UQBR (# transferable and freezable quality blastocysts/# 2PN), and PR in fresh transfer cycles were compared between clinic and home groups with t-tests. The association between time to processing on outcomes was assessed with regression modeling, controlling for potential confounders. Results Mean male age was 37.9 years in the clinic group and 37.2 years in the home group (p = 0.380). On average, men were abstinent for 3.0 days (SD 1.7) in the clinic group and 4.1 days (SD 5.4) in the home group (p = 0.028). Mean time to semen processing was 35.7 min (SD 9.4) in the clinic group and 82.6 min (SD 33.8) in the home group (p < 0.001). There was no association between collection location and increased time to processing on sperm motility, total motile count, FR, D5-UQBR, or PR. Conclusions Our data suggest that increased time to processing up to 2 h with home semen collection does not negatively impact sperm parameters or early IVF/ICSI outcomes.
Databáze: OpenAIRE
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