Analysis of rumen contents and ocular fluid for toxic alkaloids from goats and cows dosed larkspur (Delphinium barbeyi), lupine (Lupinus leucophyllus), and death camas (Zigadenus paniculatus)
| Autor: | Daniel Cook, James A. Pfister, Kevin D. Welch, Stephen T. Lee, Dale R. Gardner, Clinton A. Stonecipher |
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| Rok vydání: | 2020 |
| Předmět: |
0106 biological sciences
Rumen Biology Eye Toxicology 01 natural sciences Zigadenus Lupinus leucophyllus Death camas 03 medical and health sciences Alkaloids Animal science Animals Plant Poisoning 0303 health sciences business.industry Goats 010604 marine biology & hydrobiology Delphinium barbeyi 030302 biochemistry & molecular biology food and beverages Delphinium biology.organism_classification Lupinus Plants Toxic Toxicity Cattle Livestock business Zigadenus paniculatus |
| Zdroj: | Toxicon. 176:21-29 |
| ISSN: | 0041-0101 |
| DOI: | 10.1016/j.toxicon.2020.01.003 |
| Popis: | Larkspurs, lupines, and death camas can be acutely toxic to livestock and are serious poisonous plant problems in western North America. The toxicity of these plants depends on the composition and concentrations of the toxic alkaloids in the plants. In this study, goats and cows were dosed sub-lethal doses of larkspur, lupine, and death camas. Rumen contents and ocular fluid samples were collected, and simple extraction, sample preparation, and analytical methods were developed for the detection of toxic alkaloids in the rumen contents and ocular fluid samples. Toxic alkaloids were detected in the rumen contents and ocular fluid samples from the goats and cows dosed larkspur, lupine, and death camas. In addition, results from a case report where rumen contents were analyzed from a steer that was suspected to have died due to larkspur are reported. This demonstrates the utility of the methods described for the diagnosis of acute plant poisonings. |
| Databáze: | OpenAIRE |
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