Current status of diagnosis and treatment of bladder cancer in China – Analyses of Chinese Bladder Cancer Consortium database
| Autor: | Jielin Li, Xueyi Xue, Yaofeng Zhu, Jiongming Li, Haoqiang Shi, Fengshuo Jin, Zhiwen Chen, Jiaquan Zhou, Chengyang Li, Changli Wu, Xiangbo Kong, Kaiwen Li, Zhaowei Zhu, Changjun Yin, Shuang Huang, Longlong Fu, Jin Yang, Chaozhao Liang, Yiyi Wu, Jinchun Qi, Yinghao Sun, Zhaolin Sun, Lang Feng, Weiyang He, Ye Tian, Baiye Jin, Shan Chen, Lulin Ma, Dong Wei, Yi-Song Lv, Lei Shi, En’ci Xu, Chunxi Wang, Xin Chen, Mao Tang, Guanghou Fu, Hongfeng Guo, Xiaozhou Zhou, Guoliang Wang, Hanzhong Li, Jian Huang, Fangjian Zhou, Tiejun Pan, Yaoliang Deng, Lin Qi, Ping Han, Zhangqun Ye, Song Cen, Pu Li, Qiang Wei, Yang Liu, Benkang Shi, Hailong Hao, Jin Wen, Zhiling Zhang, Zhun Wu, Jinxin Wei, Zheng Liu, Xudong Liu, Fubao Chen, Wei Li, Zhen Du, Zhihua Lu, Wei Xue, Minfeng Chen, Dawei Tian, Xu Yang, Guangheng Luo, G. Wang, Ming Li, Xin Gou, Dongwen Wang, Chuize Kong, Hongyan Sun, Tianxin Lin, Zhoujun Shen, Zhiping Wang, Xin Mu, Shuxiong Zeng, Yongji Yan, Yan-qun Na, Lin Cai, Jianyun Hu, Liqun Zhou, Xin Gao, Guangyong Li, Jinchun Xing, Junqiang Tian, Xu Zhang |
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| Rok vydání: | 2015 |
| Předmět: |
medicine.medical_specialty
Bladder cancer medicine.diagnostic_test business.industry Urinary system medicine.medical_treatment Carcinoma in situ Urology Cystoscopy medicine.disease Article Squamous carcinoma Treatment Cystectomy medicine.anatomical_structure Diagnosis Medicine Adenocarcinoma business Lymph node GeneralLiterature_REFERENCE(e.g. dictionaries encyclopedias glossaries) ComputingMilieux_MISCELLANEOUS |
| Zdroj: | Asian Journal of Urology |
| ISSN: | 2214-3882 |
| DOI: | 10.1016/j.ajur.2015.04.016 |
| Popis: | Objective To investigate current status of diagnosis and treatment of bladder cancer in China. Methods A database was generated by Chinese Bladder Cancer Consortium (CBCC). From January 2007 to December 2012, 14,260 cases from 44 CBCC centers were included. Data of diagnosis, treatment and pathology were collected. Results The average age was 63.5 year-old and most patients were male (84.3%). The most common histologic types were urothelial carcinoma (91.4%), adenocarcinoma (1.8%), and squamous carcinoma (1.9%). According to 1973 and 2004 WHO grading system, 42.0%, 41.0%, and 17.0% of patients were grade 1, 2, and 3, and 16.0%, 48.7%, and 35.3% of patients were papillary urothelial neoplasms of low malignant potential, low, and high grade, respectively. Non-muscle invasive bladder cancer (NMIBC) and muscle invasive bladder cancer (MIBC) were 25.2% and 74.1%, respectively (0.8% not clear). Carcinoma in situ was only 2.4%. Most patients were diagnosed by white-light cystoscopy with biopsy (74.3%). Fluorescence and narrow band imaging cystoscopy had additional detection rate of 1.0% and 4.0%, respectively. Diagnostic transurethral resection (TUR) provided detection rate of 16.9%. Most NMIBCs were treated with TUR (89.2%). After initial TUR, 2.6% accepted second TUR, and 45.7%, 69.9%, and 58.7% accepted immediate, induced, and maintenance chemotherapy instillation, respectively. Most MIBCs were treated with radical cystectomy (RC, 59.7%). Laparoscopic RCs were 35.1%, while open RC 63.4%. Extended and standard pelvic lymph node dissection were 7% and 66%, respectively. Three most common urinary diversions were orthotopic neobladder (44%), ileal conduit (31%), and ureterocutaneostomy (23%). Only 2.3% of patients accepted neo-adjuvant chemotherapy and only 18% of T3 and T4 patients accepted adjuvant chemotherapy. Conclusion Disease characteristics are similar to international reports, while differences of diagnosis and treatment exist. This study can provide evidences for revisions of the guideline on bladder cancer in China. |
| Databáze: | OpenAIRE |
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