CONSECUTIVE HÆMODYNAMIC PATTERNS IN ESSENTIAL HYPERTENSION

Autor: M. A. D. H. Schalekamp, X. H. Krauss, G. Kolsters, W.H. Birkenhäger, G. A. Zaal
Rok vydání: 1972
Předmět:
Zdroj: The Lancet. 299:560-564
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(72)90356-x
Popis: Fifteen patients with essential hypertension were investigated twice (and in three cases three times), the average interval between the first and the final examination being 31 months (range 11-54 months). Arterial pressure and one or several of the following variables were measured or calculated: cardiac output, renal plasma-flow, glomerular filtration-rate, plasma volume, variability of blood-pressure, renal blood-flow, total peripheral resistance, renal vascular resistance, filtration fraction, and blood volume. In twelve patients no complications were observed. The other three had a myocardial infarction during the observation period. Patients were taken off treatment before the investigations were done and sodium intake was controlled. Even within this rather short follow-up period some radical changes in haemodynamic patterns were demonstrated. In eight of the twelve uncomplicated cases either total peripheral resistance or renal vascular resistance or both increased. The three patients who sustained a myocardial infarc tion all showed a shift towards increased vascular resistance.
Databáze: OpenAIRE